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- Table of Contents
Facts about Guanine nucleotide-binding protein G(olf) subunit alpha.
May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters. .
Human | |
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Gene Name: | GNAL |
Uniprot: | P38405 |
Entrez: | 2774 |
Belongs to: |
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G-alpha family |
Adenylate cyclase-stimulating G alpha protein, olfactory type; guanine nucleotide binding protein (G protein), alpha activating activitypolypeptide, olfactory typ; guanine nucleotide binding protein (G protein), alpha activating activitypolypeptide, olfactory type; guanine nucleotide binding protein (G protein), alpha stimulating activitypolypeptide, olfactory type; guanine nucleotide-binding protein G(olf) subunit alpha
Mass (kDA):
44.308 kDA
Human | |
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Location: | 18p11.21 |
Sequence: | 18; NC_000018.10 (11689015..11885685) |
Detected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen. Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined.
PMID: 8243272 by Zigman J.M., et al. Human G(olf) alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system.
PMID: 23994616 by Wu Y.C., et al. A novel Galphas-binding protein, Gas-2 like 2, facilitates the signaling of the A2A adenosine receptor.