GMP reductase 2 Antibodies

AND GMPR2 ELISA kits, GMP reductase 2 Proteins

Many biological assays use antibodies to detect GMP reductase 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GMP reductase 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GMP reductase 2 antibodies...

We validate the specificity of these antibodies to GMP reductase 2 by testing them on tissues known to express GMPR2 positively and negatively. Browse below to find the GMPR2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: PCDH12

GMPR2 Infographic by Boster Bio

All GMPR2 Products

Product

Figures

Specificity

Applications

Price

GMPR2 (NM_001002000) Human Recombinant Protein

$1249
Cat # PROTQ9P2T1
20 µg

GMPR2 (NM_016576) Human Over-expression Lysate

Human

$628
Cat # LS051292
100 µg

GMPR2 Overview

Facts about GMP reductase 2.

GMPR2 3D structure. Source: alphafold

GMP reductase 2 (GMPR2)

Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.
It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (PubMed:12009299, PubMed:12669231, PubMed:16359702, PubMed:22037469).

Plays a role in modulating cellular differentiation (PubMed:12669231). .

Gene Information

Human
Gene Name:	GMPR2
Uniprot:	Q9P2T1
Entrez:	51292

Family

Belongs to:

IMPDH/GMPR family

Alternative Names

EC 1.7.1.7; GMP reductase 2; Guanosine 5'-monophosphate oxidoreductase 2; guanosine monophosphate reductase 2MGC830; guanosine monophosphate reductase isolog; MGC15084

Molecular Weight

Mass (kDA):
37.874 kDA

Genomic Context


Human

Location:	14q12
Sequence:	14; NC_000014.9 (24232622..24239242)

Tissue Specificity

Highly expressed in heart, skeletal muscle, kidney, brain, liver, prostate, spleen, placenta, testis and ovary. Low expression in colon, thymus and peripheral blood leukocytes.

Diseases

Malignant Neoplasms
Neoplasms
Leukemia
Malignant Neoplasm Of Breast
Carcinogenesis
Carcinoma

Interacting Proteins

MEOX2

Pathways

Nodulation
Secretion

PTMs

Deamination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GMPR2

References

PMID: 12009299 by Deng Y., et al. NADPH-dependent GMP reductase isoenzyme of human (GMPR2). Expression, purification, and kinetic properties.

PMID: 12669231 by Zhang J., et al. Cloning and functional characterization of GMPR2, a novel human guanosine monophosphate reductase, which promotes the monocytic differentiation of HL-60 leukemia cells.