GIMAP8 Antibodies

AND GIMAP8 ELISA kits, GIMAP8 Proteins

Many biological assays use antibodies to detect GIMAP8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GIMAP8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GIMAP8 antibodies...

We validate the specificity of these antibodies to GIMAP8 by testing them on tissues known to express GIMAP8 positively and negatively. Browse below to find the GIMAP8 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GIMAP8 Infographic by Boster Bio

All GIMAP8 Products

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Product

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Specificity

Applications

Price

GIMAP8 (NM_175571) Human Recombinant Protein

$813
Cat # PROTQ8ND71
20 µg

GIMAP8 (NM_175571) Human Over-expression Lysate

Human

$960
Cat # LS155038
100 µg

GIMAP8 Overview

Facts about GTPase IMAP family member 8.

GIMAP8 3D structure. Source: alphafold

GTPase IMAP family member 8 (GIMAP8)

Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections. .

Gene Information

Human
Gene Name:	GIMAP8
Uniprot:	Q8ND71
Entrez:	155038

Family

Belongs to:

TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily

Alternative Names

DKFZp667I133; GTPase IMAP family member 8; GTPase, IMAP family member 8; hIAN6; human immune associated nucleotide 6; IAN6; IAN9; IAN-9; IANT; immune associated nucleotide; Immune-associated nucleotide-binding protein 9; MGC129545; Protein IanT

Molecular Weight

Mass (kDA):
74.89 kDA

Genomic Context


Human

Location:	7q36.1
Sequence:	7; NC_000007.14 (150450630..150479395)

Tissue Specificity

Expressed in the spleen, intestine, liver, and colon, as well as in lung, placenta, kidney, muscle, and heart. Extremely low expression, if any, in brain, in thymus, bone marrow, and blood leukocytes (PubMed:15474311). Detected in T- cells (PubMed:23454188).

Subcellular Localizations

Endoplasmic reticulum. Golgi apparatus. Mitochondrion. Cytoplasm, cytosol.

Diseases

Malignant Neoplasms
Diabetes Mellitus
Infective Disorder
Adenocarcinoma
Malignant Squamous Cell Neoplasm
Lung Neoplasms
Neoplasms
Lymphopenia
Non-small Cell Lung Carcinoma

Malaria
Diabetes Mellitus, Insulin-dependent
Malignant Neoplasm Of Lung

Pathways

T Cell Homeostasis
Pathogenesis
Localization

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GIMAP8

References

PMID: 16103028 by Dion C., et al. Expression of the Ian family of putative GTPases during T cell development and description of an Ian with three sets of GTP/GDP- binding motifs.

PMID: 15474311 by Kruecken J., et al. Comparative analysis of the human gimap gene cluster encoding a novel GTPase family.