GGCT Antibodies

AND GGCT ELISA kits, GGCT Proteins

Many biological assays use antibodies to detect GGCT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GGCT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GGCT antibodies...

We validate the specificity of these antibodies to GGCT by testing them on tissues known to express GGCT positively and negatively. Browse below to find the GGCT antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GGCT Infographic by Boster Bio

All GGCT Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Gamma-glutamylcyclotransferase GGCT Antibody

Human

$405
Cat # A06488
100ul

Anti-Gamma-glutamylcyclotransferase GGCT Antibody

Human, Mouse

ELISA, WB

$380
Cat # A06488-1
100ul

GGCT (NM_024051) Human Recombinant Protein

$813
Cat # PROTO75223
20 µg

GGCT (NM_024051) Human Over-expression Lysate

Human

$628
Cat # LS079017
100 µg

Human GGCT/CRF21 ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2205
96 wells/kit, with removable strips.

GGCT Overview

Facts about Gamma-glutamylcyclotransferase.

GGCT 3D structure. Source: alphafold

Gamma-glutamylcyclotransferase (GGCT)

Catalyzes the formation of 5-oxoproline from gamma- glutamyl dipeptides and might play a substantial role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.

Gene Information

Human
Gene Name:	GGCT
Uniprot:	O75223
Entrez:	79017

Family

Belongs to:

gamma-glutamylcyclotransferase family

Alternative Names

C7orf24; CRF21; gammaGlutamylcyclotransferase; gamma-Glutamylcyclotransferase; GCTG; GGC; GGCT; LOC79017; MGC3077

Molecular Weight

Mass (kDA):
21.008 kDA

Genomic Context


Human

Location:	7p14.3
Sequence:	7; NC_000007.14 (30496621..30504841, complement)

Diseases

Malignant Neoplasms
Neoplasms
Autoimmune Reaction
Malignant Neoplasm Of Lung
Diabetes Mellitus
Diabetes Mellitus, Insulin-dependent
Carcinoma
Nutrition Disorders
Lung Neoplasms
Cholangiocarcinoma
Autoimmunity

Malnutrition
Eating Disorders
Behcet Syndrome
Tumor Progression
Malignant Neoplasm Of Breast
Inflammatory Response

Pathways

Pathogenesis
Cell Proliferation
Cell Cycle
M Phase
Localization
Inflammatory Response

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GGCT

References

PMID: 16765912 by Masuda Y., et al. A novel 21-kDa cytochrome c-releasing factor is generated upon treatment of human leukemia U937 cells with geranylgeraniol.

PMID: 18515354 by Oakley A.J., et al. The identification and structural characterization of C7orf24 as gamma-glutamyl cyclotransferase: an essential enzyme in the gamma- glutamyl cycle.