Lysophospholipase D GDPD3 (Gdpd3)

Hydrolyzes lysoglycerophospholipids to generate lysophosphatidic acid (LPA) and the corresponding amines (PubMed:25528375). Shows a preference for 1-O-alkyl-sn-glycero-3- phosphocholine (lyso-PAF) and lysophosphatidylcholine (lyso-PC), and to a lesser extent for lysophosphatidylethanolamine (lyso-PE) (PubMed:25528375).

Doesn't display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine (PubMed:25528375). .