GDF2 Antibodies

Growth/differentiation factor 2 (GDF2)

Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks.

Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. .

Gene Information

Human
Gene Name:	GDF2
Uniprot:	Q9UK05
Entrez:	2658

Family

Belongs to:
TGF-beta family

Alternative Names

BMP9; BMP-9; BMP9BMP-9Bone morphogenetic protein 9; GDF2; GDF-2; growth differentiation factor 2; growth/differentiation factor 2

Molecular Weight

Mass (kDA):
47.32 kDA

Genomic Context

Human
Location:	10q11.22
Sequence:	10; NC_000010.11 (47322454..47327588)

Tissue Specificity

Detected in blood plasma (at protein level).

Subcellular Localizations

Secreted.

Diseases

• Tumor Angiogenesis
• Neoplasms
• Hereditary Hemorrhagic Telangiectasia
• Telangiectasis
• Malignant Neoplasms
• Pathologic Neovascularization
• Tissue Adhesions
• Neoplasm Metastasis
• Dysplasia
• Bone Diseases
• Cytomegalovirus Infections
• Metastatic Malignant Neoplasm To The Bone

• Heterotopic Ossification
• Diabetes Mellitus
• Nervousness
• Cell Invasion
• Iron Overload
• Cholangiocarcinoma
• Malignant Neoplasm Of Breast

Pathways

• Angiogenesis
• Regeneration
• Cell Proliferation
• Cell Migration
• Osteoblast Differentiation
• Ossification
• Bmp Signaling Pathway
• Tissue Regeneration
• Immune Response
• Cell Differentiation
• Endothelial Cell Migration
• Regulation Of Angiogenesis
• Pathogenesis

• Secretion
• Gene Silencing
• Tube Formation
• Endothelial Cell Proliferation
• Glucose Homeostasis
• Translation
• Bioluminescence

PTMs

• Phosphorylation

• Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GDF2

Best Uses Of The GDF2 Marker

Continue reading if you want to learn more on Steven Boster and the primary antibody he discovered. Here are some uses for the GDF2 markers and some of Boster’s main antibodies. A list of Boster's most cited primary antibody will also be provided. Continue reading to learn how to make the most of these antibodies, and what other scientists have discovered about them.

His primary antibodies

His primary antibodies were raised in response to peptides specific to the GDF2 gene. The cells were incubated in 4% formaldehyde-in PBS for 15 minutes at room temperatures, then permeabilized by 1% saponin. Finally, the cells were incubated in primary antibodies for 3 hours at roomtemperature. The antibodies were used at dilutions of 1:100.

Citations

The use of Bioz technology, a fusion of Natural Language Processing (NLP) and Machine Learning (ML), is a powerful way to uncover the best real-world use-cases of scientific papers and provide relevant context to researchers. Boster Bio utilizes this technology by displaying the most recent relevant product-citations. Boster Bio products have citations from more than 29,000 scientific publications.

Boster Bio is a leader in the manufacture of antibodies and ELISA kits for researchers. Boster Bio has more than 20 years of experience, and their products have received over 14000 citations. Boster Bio specializes on antibody and ELISA kits to detect biomarkers of cancer, neuroscience, inflammation, and other diseases. Boster Bio products are highly sensitive and can be ordered through tebu–bio. The company recently appointed LAB-A-PORTER Limited, as the official distributor of Boster Bio products in all parts of the globe.

Boster Bio is a specialist in high-sensitivity ELISA kit development and IHC-optimized, polyclonal antibody development. Boster Bio has over 12,000 high affinity antibodies in its product line. Boster Bio antibodies are tested against over 250 tissue samples. This validates their high affinity. Additionally, Boster Bio antibody products are backed by the Boster Quality Guarantee.