GCNT2 Antibodies

AND GCNT2 ELISA kits, GCNT2 Proteins

Many biological assays use antibodies to detect GCNT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GCNT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GCNT2 antibodies...

We validate the specificity of these antibodies to GCNT2 by testing them on tissues known to express GCNT2 positively and negatively. Browse below to find the GCNT2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GCNT2 Infographic by Boster Bio

All GCNT2 Products

Product

Figures

Specificity

Applications

Price

GCNT2 (NM_145655) Human Recombinant Protein

$1249
Cat # PROTQ8N0V5
20 µg

GCNT2 (NM_145649) Human Over-expression Lysate

Human

$628
Cat # LS002651
100 µg

GCNT2 Overview

Facts about N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase.

GCNT2 3D structure. Source: alphafold

N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (GCNT2)

Branching enzyme that converts linear into branched poly-N-acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development.

It's closely associated with the development and maturation of erythroid cells. .

Gene Information

Human
Gene Name:	GCNT2
Uniprot:	Q8N0V5
Entrez:	2651

Family

Belongs to:

glycosyltransferase 14 family

Alternative Names

bA360O19.2; bA421M1.1; beta-1,6-N-acetylglucosaminyltransferase 2; cataract, congenital; CCAT; EC 2.4.1.150; GCNT2C; GCNT5; glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group); glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (Ii blood group); glucosaminyl (N-acetyl) transferase 2, I-branching enzyme; I beta-1,6-N-acetylglucosaminyltransferase; I-branching beta-1,6-acetylglucosaminyltransferase; I-branching enzyme; IGNTglucosaminyl (N-acetyl) transferase 5; Ii blood group; II; MGC163396; N-acetylglucosaminyltransferase; N-acetyllactosaminide beta-1,6-N-acetylgluc

Molecular Weight

Mass (kDA):
45.873 kDA

Genomic Context


Human

Location:	6p24.3-p24.2
Sequence:	6; NC_000006.12 (10521283..10629368)

Tissue Specificity

Isoform B is expressed in lens epithelium cells. Isoform C is expressed in reticulocytes.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Cataract
Cell Invasion
Neoplasm Metastasis
Lung Neoplasms
Metastatic Malignant Neoplasm To The Lung
Malignant Neoplasm Of Breast
Schizophrenia
Idiopathic Hypereosinophilic Syndrome
Tissue Adhesions
Neoplasm Invasiveness
Diabetes Mellitus
Iron Metabolism Disorders

Autoimmune Reaction
Disorder Of Eye
Malignant Neoplasms
Neoplasms
Diabetes Mellitus, Insulin-dependent
Mammary Neoplasms
Dog Diseases

Pathways

Gene Conversion
Cell Migration
Glycosylation

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GCNT2

References

PMID: 8449405 by Bierhuizen M.F.A., et al. Expression of the developmental I antigen by a cloned human cDNA encoding a member of a beta-1,6-N-acetylglucosaminyltransferase gene family.

PMID: 7579796 by Bierhuizen M.F.A., et al. Genomic organization of core 2 and I branching beta-1,6-N- acetylglucosaminyltransferases. Implication for evolution of the beta- 1,6-N-acetylglucosaminyltransferase gene family.