Transcription factor 12 Antibodies

AND TCF12 ELISA kits, Transcription factor 12 Proteins

Many biological assays use antibodies to detect Transcription factor 12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transcription factor 12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transcription factor 12 antibodies...

We validate the specificity of these antibodies to Transcription factor 12 by testing them on tissues known to express TCF12 positively and negatively. Browse below to find the TCF12 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TCF12 Infographic by Boster Bio

All TCF12 Products

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Product

Figures

Specificity

Applications

Price

Anti-Transcription factor 12 TCF12 Antibody

Human, Mouse, Rat

ELISA, ICC, WB

$449
Cat # A02592
0.1 mg

Anti-TCF12 Mouse Monoclonal Antibody [Clone ID: OTI4D6]

Human, Mouse, Rat

IHC, WB

$523
Cat # M02592
100 µl

TCF12 (NM_207036) Human Over-expression Lysate

Human

$960
Cat # LS006938
100 µg

Anti-HEB/TCF12 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A02592-3
100 μg/vial

TCF12 Overview

Facts about Transcription factor 12.

TCF12 3D structure. Source: alphafold

Transcription factor 12 (TCF12)

Transcriptional regulator. Involved in the initiation of neuronal differentiation.

Activates transcription by binding to the E box (5'-CANNTG-3'). .

Gene Information

Human
Gene Name:	TCF12
Uniprot:	Q99081
Entrez:	6938

Family

Belongs to:

No superfamily

Alternative Names

BHLHB20; bHLHb20E-box-binding protein; Class B basic helix-loop-helix protein 20; HEB; HEBDNA-binding protein HTF4; helix-loop-helix transcription factor 4; HsT17266; HTF4; HTF4TCF-12; TCF12; TCF-12; transcription factor 12; Transcription factor HTF-4

Molecular Weight

Mass (kDA):
72.965 kDA

Genomic Context


Human

Location:	15q21.3
Sequence:	15; NC_000015.10 (56918090..57292595)

Tissue Specificity

Expressed in several tissues and cell types including skeletal muscle, thymus, and a B-cell line.

Subcellular Localizations

Nucleus.

Diseases

Leukemia
Neoplasms
Lymphohistiocytosis, Hemophagocytic
Precursor T-cell Lymphoblastic Leukemia-lymphoma
Acute Lymphocytic Leukemia
Malignant Neoplasms
Adult T-cell Lymphoma/leukemia
Myeloid Leukemia
Chromosomal Translocation
Leukemia, Myelocytic, Acute
Cell Transformation, Neoplastic
Leukemogenesis

Chondrosarcoma
Lymphoma
T-cell Lymphoma
Bone Neoplasms
Nervousness
Neoplasm Metastasis
Dyslexia

Interacting Proteins

ARMC8
ASCL4
C16orf45
C1orf109
CDKN2C

CFAP206
CRCP
FOXH1
HEXIM2
HOPX

ID2
ID3
LYSMD1
MAPKBP1
MORN4

NAGK
NEUROD1
NEUROG3
OSGIN1
PSMA1

QARS
SPG21
SRI
STAT5A
STK16

TAL1
TRIM72
TSNAX
TWIST2
VPS28

Pathways

Cell Development
Cell Differentiation
T Cell Differentiation
Neurogenesis
V(d)j Recombination
Brain Development
Oncogenesis
Cell Proliferation
Aging
Cell Cycle
Oligodendrocyte Development
Gastrulation
Pathogenesis

Granulocyte Differentiation
Cell Migration
Muscle Cell Differentiation
Quorum Sensing
Tube Formation
Immune Response
Regulation Of Gene Expression

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TCF12

References

PMID: 1446075 by Zhang Y., et al. The nucleotide sequence of the human transcription factor HTF4a cDNA.

PMID: 1312219 by Hu J.S., et al. HEB, a helix-loop-helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory factors.