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GCDH Antibodies

AND GCDH ELISA kits, GCDH Proteins

Many biological assays use antibodies to detect GCDH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GCDH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GCDH antibodies...

We validate the specificity of these antibodies to GCDH by testing them on tissues known to express GCDH positively and negatively. Browse below to find the GCDH antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GCDH Infographic by Boster Bio

GCDH protein infographic

All GCDH Products

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Product

Figures

Specificity

Applications

Price

Anti-GCDH Antibody

Human, Mouse, Rat

WB

$405
Cat # A03139
100ul

GCDH (NM_000159) Human Recombinant Protein

$813
Cat # PROTQ92947
20 µg

GCDH Overview

Facts about Glutaryl-CoA dehydrogenase, mitochondrial.

GCDH 3D structure

GCDH 3D structure. Source: alphafold

Glutaryl-CoA dehydrogenase, mitochondrial (GCDH)

Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor.

Isoform Short is dormant. .

Gene Information

Human
Gene Name:	GCDH
Uniprot:	Q92947
Entrez:	2639

Gene Information

Family

Belongs to:

acyl-CoA dehydrogenase family

Family

Alternative Names

ACAD5; EC 1.3.99; EC 1.3.99.7; GCD; glutaryl-CoA dehydrogenase; glutaryl-CoA dehydrogenase, mitochondrial; glutaryl-Coenzyme A dehydrogenase

Molecular Weight

Mass (kDA):
48.127 kDA

Molecular Weight

Genomic Context


Human

Location:	19p13.13
Sequence:	19; NC_000019.10 (12891129..12915345)

Tissue Specificity

Isoform Long and isoform Short are expressed in fibroblasts and liver.

Subcellular Localizations

Mitochondrion matrix.

Subcellular Localization

Diseases

Glutaric Aciduria, Type 1
Dystonia Disorders
Acidemia
Inborn Errors Of Metabolism
Macrocephaly
Movement Disorders
Atrophy
Brain Diseases, Metabolic
Brain Diseases, Metabolic, Inborn
Brain Injuries
Nervous System Disorder

Dyskinetic Syndrome
Nerve Degeneration
Encephalopathies
Muscle Hypotonia
Neurodegenerative Disorders
Sequelae Aspects

Disease

Pathways

Excretion
Transport
Pathogenesis
Succinate Transport
Host-pathogen Interaction
Chromosome Localization
Cell Proliferation
Translation
Tricarboxylic Acid Cycle

Cell Death
Localization
Myelination

Pathways

PTMs

Oxidation
Carboxylation

Reduction
Decarboxylation

Research Areas

Stem Cell Markers

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GCDH

References

PMID: 1438360 by Goodman S.I., et al. Pork and human cDNAs encoding glutaryl-CoA dehydrogenase.

PMID: 8541831 by Goodman S.I., et al. Cloning of glutaryl-CoA dehydrogenase cDNA, and expression of wild type and mutant enzymes in Escherichia coli.