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- Table of Contents
Facts about Guanylate-binding protein 3.
Human | |
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Gene Name: | GBP3 |
Uniprot: | Q9H0R5 |
Entrez: | 2635 |
Belongs to: |
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TRAFAC class dynamin-like GTPase superfamily |
DKFZp686E0974; DKFZp686L15228; FLJ10961; GBP-3; GTP-binding protein 3; Guanine nucleotide-binding protein 3; guanylate binding protein 3; guanylate-binding protein 3
Mass (kDA):
68.114 kDA
Human | |
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Location: | 1p22.2 |
Sequence: | 1; NC_000001.11 (89006677..89022870, complement) |
Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus membrane. Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus.
PMID: 22106366 by Nordmann A., et al. A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication.
PMID: 17266443 by Tripal P., et al. Unique features of different members of the human guanylate-binding protein family.