GATAD2B Antibodies

AND GATAD2B ELISA kits, GATAD2B Proteins

Many biological assays use antibodies to detect GATAD2B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GATAD2B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GATAD2B antibodies...

We validate the specificity of these antibodies to GATAD2B by testing them on tissues known to express GATAD2B positively and negatively. Browse below to find the GATAD2B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GATAD2B Infographic by Boster Bio

All GATAD2B Products

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Product

Figures

Specificity

Applications

Price

Anti-GATAD2B Antibody

Human, Mouse, Rat

IP, IHC, WB

$405
Cat # A07417
100ul

p66 beta (GATAD2B) (NM_020699) Human Over-expression Lysate

Human

$628
Cat # LS057459
100 µg

GATAD2B Overview

Facts about Transcriptional repressor p66-beta.

GATAD2B 3D structure. Source: alphafold

Transcriptional repressor p66-beta (GATAD2B)

Transcriptional repressor. Enhances MBD2-mediated repression.

Efficient repression requires the existence of GATAD2A. Targets MBD3 to discrete loci in the nucleus.

Gene Information

Human
Gene Name:	GATAD2B
Uniprot:	Q8WXI9
Entrez:	57459

Family

Belongs to:

No superfamily

Alternative Names

FLJ37346; GATA zinc finger domain containing 2B; GATA zinc finger domain-containing protein 2B; KIAA1150; MGC138257; MGC138285; p66/p68; P66beta; RP11-216N14.6; transcription repressor p66 beta component of the MeCP1 complex; transcriptional repressor p66-beta

Molecular Weight

Mass (kDA):
65.261 kDA

Genomic Context


Human

Location:	1q21.3
Sequence:	1; NC_000001.11 (153804725..153923953, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Nucleus speckle. Speckled nuclear localization requires both CR1 and CR2 regions.

Diseases

Mouth Neoplasms
Dysplasia
Malignant Squamous Cell Neoplasm
Fracture
Cell Transformation, Neoplastic
Malignant Neoplasms
Osteoporotic Fractures
Neoplasms

Osteoporosis
Dysequilibrium Syndrome
Carcinoma

Interacting Proteins

CALCOCO2
CEP70
GOLGA2
MBD3
PRKAB2

RPGRIP1
TEX11
TRAF1
TRIM27
USHBP1

ZBTB7A
ZNF827

Pathways

Transport
Nuclear Transport

PTMs

Isopeptide bond

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GATAD2B

References

PMID: 11756549 by Feng Q., et al. Identification and functional characterization of the p66/p68 components of the MeCP1 complex.

PMID: 12183469 by Brackertz M., et al. Two highly related p66 proteins comprise a new family of potent transcriptional repressors interacting with MBD2 and MBD3.