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- Table of Contents
Facts about H/ACA ribonucleoprotein complex subunit 1.
This involves the isomerization of uridine such that the ribose is then attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may function to stabilize the conformation of rRNAs.
Human | |
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Gene Name: | GAR1 |
Uniprot: | Q9NY12 |
Entrez: | 54433 |
Belongs to: |
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GAR1 family |
GAR1 ribonucleoprotein homolog (yeast); H/ACA ribonucleoprotein complex subunit 1; NOLA1member 1 (H/ACA small nucleolar RNPs); Nucleolar protein family A member 1; snoRNP protein GAR1
Mass (kDA):
22.348 kDA
Human | |
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Location: | 4q25 |
Sequence: | 4; NC_000004.12 (109815510..109824737) |
Nucleus, nucleolus. Nucleus, Cajal body. Also localized to Cajal bodies (coiled bodies).
PMID: 10757788 by Dragon F., et al. In vitro assembly of human H/ACA small nucleolar RNPs reveals unique features of U17 and telomerase RNAs.
PMID: 11509230 by Pellizzoni L., et al. The survival of motor neurons (SMN) protein interacts with the snoRNP proteins fibrillarin and GAR1.