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- Table of Contents
Facts about Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5.
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Mouse | |
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Gene Name: | Galntl5 |
Uniprot: | Q9D4M9 |
Entrez: | 67909 |
Belongs to: |
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glycosyltransferase 2 family |
EC 2.4.1.-; EC 2.4.1.41; galNAc-T15; GALNT15; Polypeptide GalNAc transferase 15; pp-GaNTase 15; Protein-UDP acetylgalactosaminyltransferase 15; putative polypeptide N-acetylgalactosaminyltransferase-like protein 5; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 15; UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 15; UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase-like 5
Mass (kDA):
49.874 kDA
Mouse | |
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Location: | 5|5 A3 |
Sequence: | 5; |
Expressed in testis. Mainly expressed in the round and elongated spermatids during spermiogenesis, not in the outermost cells of the seminiferous tubules, which contain spermatogonia and somatic Sertoli cells. Present in the juxtanuclear space in the round spermatids, not in the acrosomal vesicles. In the elongating spermatids, localizes strongly in the acroplaxome, the region between the developing acrosome and nucleus. During differentiation, also weakly detected in the transient manchette containing microtubules. In epididymal spermatozoa, weakly detected in the midpiece, but concentrates mainly in the neck region around the head-tail coupling apparatus (at protein level).
PMID: 24398516 by Takasaki N., et al. A heterozygous mutation of GALNTL5 affects male infertility with impairment of sperm motility.