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- Table of Contents
Facts about Polypeptide N-acetylgalactosaminyltransferase 4.
Glycosylates 'Thr-57' of SELPLG. .
Human | |
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Gene Name: | GALNT4 |
Uniprot: | Q8N4A0 |
Entrez: | 8693 |
Belongs to: |
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glycosyltransferase 2 family |
EC 2.4.1.41; FLJ93314; GALNACT4; GalNAc-T4; GALNT4; Polypeptide GalNAc transferase 4; polypeptide N-acetylgalactosaminyltransferase 4; pp-GaNTase 4; Protein-UDP acetylgalactosaminyltransferase 4; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4; UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 4 (GalNAc-T4)
Mass (kDA):
66.666 kDA
Human | |
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Location: | 12q21.33 |
Sequence: | 12; NC_000012.12 (89519412..89524796, complement) |
Ubiquitous. Highly expressed in mucous cells.
Golgi apparatus membrane; Single-pass type II membrane protein.
PMID: 9804815 by Bennett E.P., et al. Cloning of a human UDP-N-acetyl-alpha-D-Galactosamine:polypeptide N- acetylgalactosaminyltransferase that complements other GalNAc- transferases in complete O-glycosylation of the MUC1 tandem repeat.
PMID: 10984485 by Hassan H., et al. The lectin domain of UDP-N-acetyl-D-galactosamine: polypeptide N- acetylgalactosaminyltransferase-T4 directs its glycopeptide specificities.