GAL3ST1 Antibodies

AND GAL3ST1 ELISA kits, GAL3ST1 Proteins

Many biological assays use antibodies to detect GAL3ST1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GAL3ST1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GAL3ST1 antibodies...

We validate the specificity of these antibodies to GAL3ST1 by testing them on tissues known to express GAL3ST1 positively and negatively. Browse below to find the GAL3ST1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GAL3ST1 Infographic by Boster Bio

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GAL3ST1 (NM_004861) Human Over-expression Lysate

Human

$628
Cat # LS009514
100 µg

GAL3ST1 Overview

Facts about Galactosylceramide sulfotransferase.

GAL3ST1 3D structure. Source: alphafold

Galactosylceramide sulfotransferase (GAL3ST1)

Catalyzes the sulfation of membrane glycolipids. Seems to prefer beta-glycosides in the non-reducing termini of sugar chains attached to a lipid moiety.

Catalyzes the synthesis of galactosylceramide sulfate (sulfatide), a major lipid component of the myelin sheath and of monogalactosylalkylacylglycerol sulfate (seminolipid), present in spermatocytes (By similarity). Also acts on lactosylceramide, galactosyl 1-alkyl-2-sn-glycerol and galactosyl diacylglycerol (in vitro).

Gene Information

Human
Gene Name:	GAL3ST1
Uniprot:	Q99999
Entrez:	9514

Family

Belongs to:

galactose-3-O-sulfotransferase family

Alternative Names

3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase; 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase; cerebroside (3'-phosphoadenylylsulfate:galactosylceramide 3') sulfotransferase; CSTCerebroside sulfotransferase; EC 2.8.2.11; galactose-3-O-sulfotransferase 1; galactosylceramide sulfotransferase; GalCer sulfotransferase

Molecular Weight

Mass (kDA):
48.764 kDA

Genomic Context


Human

Location:	22q12.2
Sequence:	22; NC_000022.11 (30554635..30574665, complement)

Tissue Specificity

Expressed in kidney proximal tubule, gastric mucosa and adenocarcinoma. Highly expressed in renal cell carcinoma cell lines.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Schizophrenia
Nervous System Disorder
Atrophy
Tissue Adhesions
Subfertility
Nematode Infections
Atrophy Of Testis
Carcinoma
Chronic Schizophrenia
Malignant Neoplasms
Neoplasms

Malignant Neoplasm Of Ovary
Epithelial Ovarian Cancer
Lipid Metabolism Disorders
Ovarian Neoplasm
Hyperplasia

Pathways

Meiosis
Spermatogenesis
Cell Death
Localization
Myelination

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GAL3ST1

References

PMID: 9030544 by Honke K., et al. Molecular cloning and expression of cDNA encoding human 3'- phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase.

PMID: 10785389 by Tsuda M., et al. Cancer-associated alternative usage of multiple promoters of human GalCer sulfotransferase gene.