FIS1 Antibodies

AND FIS1 ELISA kits, FIS1 Proteins

Many biological assays use antibodies to detect FIS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FIS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FIS1 antibodies...

We validate the specificity of these antibodies to FIS1 by testing them on tissues known to express FIS1 positively and negatively. Browse below to find the FIS1 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FIS1 Infographic by Boster Bio

All FIS1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TTC11/FIS1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01932-2
100 μg/vial

Anti-FIS1 Antibody

Human, Mouse, Rat

IP, IF, ICC, WB

$405
Cat # A01932
100ul

Human TTC11 Recombinant Protein

SDS-PAGE

$243
Cat # PROTQ9Y3D6
Starting from 20ug

Anti-TTC11 Rabbit Monoclonal Antibody

Human

IF, IHC, ICC, WB

$370
Cat # M01932-1
100 μl/vial

Anti-TTC11/FIS1 Antibody Picoband®

Human, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A01932-3
100 μg/vial

Anti-Fruit fly Fis1 Antibody

Fruit fly

$470
Cat # DZ41318
200 μl/vial

TTC11 (FIS1) (NM_016068) Human Over-expression Lysate

Human

$628
Cat # LS051024
100 µg

FIS1 Overview

Facts about Mitochondrial fission 1 protein.

FIS1 3D structure. Source: alphafold

Mitochondrial fission 1 protein (FIS1)

Involved from the fragmentation of the mitochondrial system and its perinuclear clustering. Plays a minor part in the recruitment and institution of the fission mediator dynamin- associated protein 1 (DNM1L) into the mitochondrial surface and mitochondrial fission.

Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.

Gene Information

Human
Gene Name:	FIS1
Uniprot:	Q9Y3D6
Entrez:	51024

Family

Belongs to:

FIS1 family

Alternative Names

CGI-135; FIS1 homolog; Fis1; fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae); fission 1 (mitochondrial outer membrane) homolog (yeast); H_NH0132A01.6; hFis1; mitochondrial fission 1 protein; tetratricopeptide repeat domain 11; Tetratricopeptide repeat protein 11; TTC11TPR repeat protein 11

Molecular Weight

Mass (kDA):
16.938 kDA

Genomic Context


Human

Location:	7q22.1
Sequence:	7; NC_000007.14 (101239472..101245081, complement)

Subcellular Localizations

Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.

Diseases

Atrophy
Malignant Neoplasms
Parkinson Disease
Neurodegenerative Disorders
Optic Atrophy
Alzheimer's Disease
Multiple Endocrine Neoplasia
Optic Atrophy, Autosomal Dominant
Diabetes Mellitus
Nerve Degeneration
Hypoxia
Neoplasms
Plant Diseases

Impaired Cognition
Myocardial Infarction
Anoxia
Neuroblastoma
Mitochondrial Diseases
Charcot-marie-tooth Disease
Ischemia

Interacting Proteins

BCAP31
CCDC155
MIEF1
NOD2

Pathways

Mitochondrial Fission
Cell Death
Mitochondrial Fusion
Autophagy
Pathogenesis
Seed Development
Membrane Fission
Organelle Fission
Transport
Programmed Cell Death
Rna Interference
Fertilization
Aging

Oxidative Phosphorylation
Localization
Endosperm Development
Cell Growth
Regulation Of Mitochondrial Fission
Peroxisome Fission
Senescence

PTMs

Phosphorylation
Cleavage
Ubiquitination

Sumoylation
Nitrosylation
Methylation

Research Areas

Apoptosis
Cancer
Mitochondrial Fusion Proteins
Tumor Suppressors

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FIS1

References

PMID: 12783892 by James D.I., et al. hFis1, a novel component of the mammalian mitochondrial fission machinery.

PMID: 12861026 by Yoon Y., et al. The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1.