FUT6 Antibodies

AND FUT6 ELISA kits, FUT6 Proteins

Many biological assays use antibodies to detect FUT6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FUT6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FUT6 antibodies...

We validate the specificity of these antibodies to FUT6 by testing them on tissues known to express FUT6 positively and negatively. Browse below to find the FUT6 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FUT6 Infographic by Boster Bio

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Anti-FUT6 Antibody

Human

IHC, WB

$405
Cat # A06862
100ul

FUT6 Overview

Facts about Alpha-(1,3)-fucosyltransferase 6.

FUT6 3D structure. Source: alphafold

Alpha-(1,3)-fucosyltransferase 6 (FUT6)

Enzyme involved in the biosynthesis of this E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP- beta-fucose into alpha-2,3 sialylated substrates.

Gene Information

Human
Gene Name:	FUT6
Uniprot:	P51993
Entrez:	2528

Family

Belongs to:

glycosyltransferase 10 family

Alternative Names

alpha-(1,3)-fucosyltransferase; EC 2.4.1; FCT3A; FCT3AFuc-TVI; FLJ40754; FT1A; fucosyltransferase 6 (alpha (1,3) fucosyltransferase); Fucosyltransferase 6; Fucosyltransferase VI; Fuc-TVI; FucT-VIEC 2.4.1.65; FUT6; Galactoside 3-L-Fucosyltransferase

Molecular Weight

Mass (kDA):
41.86 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (5830408..5840019, complement)

Tissue Specificity

Kidney, liver, colon, small intestine, bladder, uterus and salivary gland.

Subcellular Localizations

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Membrane-bound form in trans cisternae of Golgi.

Diseases

Carcinoma
Lupus Erythematosus, Systemic
Malignant Neoplasms
Neoplasms
Liver Carcinoma
Tissue Adhesions
Liver Neoplasms
Colonic Neoplasms
Malignant Tumor Of Colon
Malignant Neoplasm Of Lung
Cytomegalovirus Infections
Lung Neoplasms

Schizophrenia
Malignant Paraganglionic Neoplasm
Stomach Neoplasms
Coronary Heart Disease
Neurodegenerative Disorders
Tumor Progression
Anemia, Pernicious

Pathways

Fucosylation
Glycosylation
Cell Adhesion
Cell Proliferation
Protein Folding
Cell Growth
Secretion
Gene Silencing
Dna Methylation
Tropism
Protein Deacetylation

Methylation
Protein Glycosylation
Dna Replication
Translation
Pathogenesis

PTMs

Glycosylation
Phosphorylation

Cleavage
Deacetylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FUT6

References

PMID: 1520296 by Koszdin K.L., et al. The cloning and expression of a human alpha-1,3 fucosyltransferase capable of forming the E-selectin ligand.

PMID: 1339443 by Weston B.W., et al. Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes.