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- Table of Contents
Facts about FERM and PDZ domain-containing protein 2.
.
Human | |
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Gene Name: | FRMPD2 |
Uniprot: | Q68DX3 |
Entrez: | 143162 |
Belongs to: |
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No superfamily |
FERM and PDZ domain containing 2
Mass (kDA):
144.282 kDA
Human | |
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Location: | 10q11.22 |
Sequence: | 10; NC_000010.11 (48156559..48274696, complement) |
Expressed in epithelial cells.
Cytoplasm. Basolateral cell membrane. Cell junction, tight junction. Colocalizes with CTNNB1, CDH1 and PKP4 at the basolateral membrane. Colocalizes with TJP1 at tight junctions. Its recruitment to cell-cell contacts requires CDH1.
PMID: 19706687 by Stenzel N., et al. PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells.
PMID: 22068589 by Khan K., et al. Next generation sequencing identifies mutations in Atonal homolog 7 (ATOH7) in families with global eye developmental defects.