FRMD7 Antibodies

AND FRMD7 ELISA kits, FRMD7 Proteins

Many biological assays use antibodies to detect FRMD7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FRMD7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FRMD7 antibodies...

We validate the specificity of these antibodies to FRMD7 by testing them on tissues known to express FRMD7 positively and negatively. Browse below to find the FRMD7 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FRMD7 Infographic by Boster Bio

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FRMD7 (NM_194277) Human Over-expression Lysate

Human

$960
Cat # LS090167
100 µg

FRMD7 Overview

Facts about FERM domain-containing protein 7.

FRMD7 3D structure. Source: alphafold

FERM domain-containing protein 7 (FRMD7)

Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability.

Gene Information

Human
Gene Name:	FRMD7
Uniprot:	Q6ZUT3
Entrez:	90167

Family

Belongs to:

No superfamily

Alternative Names

FERM domain containing 7; FLJ43346

Molecular Weight

Mass (kDA):
81.614 kDA

Genomic Context


Human

Location:	Xq26.2
Sequence:	X; NC_000023.11 (132074926..132128022, complement)

Tissue Specificity

Expressed in liver, kidney, pancreas and at low levels in brain and heart. Expressed in embryonic brain and developing neural retina.

Subcellular Localizations

Cell projection, neuron projection. Cell projection, growth cone. In undifferentiated neurons, located in the actin-rich regions of the cell body. In differentiated neurons, located in the actin-rich regions of the cell body and primary neurite processes but is almost absent from secondary extensions arising from the primary neurite. Also found at the actin-rich distal end of growth cones (By similarity).

Diseases

Nystagmus
Congenital Nystagmus
Genetic Diseases, X-linked
Albinism
Congenital Nystagmus Without Sensory Abnormality
Albinism, Ocular
Hypoplasia
Neuroblastoma
Pendular Nystagmus
Strabismus
Eye Diseases, Hereditary
Jerk Nystagmus

Congenital Mesoblastic Nephroma
Ocular Motility Disorders
Movement Disorders
Retinal Dystrophies
Periodic Alternating Nystagmus
Malnutrition

Pathways

Pathogenesis
Methylation
Cell Differentiation
Localization
Reflex

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FRMD7

References

PMID: 22128244 by Li Y., et al. Identification of a novel FRMD7 splice variant and functional analysis of two FRMD7 transcripts during human NT2 cell differentiation.

PMID: 19892780 by Betts-Henderson J., et al. The nystagmus-associated FRMD7 gene regulates neuronal outgrowth and development.