FRAS1 Antibodies

AND FRAS1 ELISA kits, FRAS1 Proteins

Many biological assays use antibodies to detect FRAS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FRAS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FRAS1 antibodies...

We validate the specificity of these antibodies to FRAS1 by testing them on tissues known to express FRAS1 positively and negatively. Browse below to find the FRAS1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FRAS1 Infographic by Boster Bio

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FRAS1 Overview

Facts about Extracellular matrix protein FRAS1.

Extracellular matrix protein FRAS1 (FRAS1)

Gene Information

Human
Gene Name:	FRAS1
Uniprot:	Q86XX4
Entrez:	80144

Family

Belongs to:

FRAS1 family

Alternative Names

DKFZp686I05113; extracellular matrix protein FRAS1; FLJ14927; FLJ22031; Fraser syndrome 1; KIAA1500DKFZp686P08111

Molecular Weight

Mass (kDA):
443.214 kDA

Genomic Context


Human

Location:	4q21.21
Sequence:	4; NC_000004.12 (78057323..78544269)

Tissue Specificity

Expressed in many adult tissues, with highest levels in kidney, pancreas and thalamus. Relatively high expression was also detected in fetal kidney and heart.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein; Extracellular side.

Diseases

Cryptophthalmos Syndrome
Bulla
Cryptophthalmos
Syndactyly
Congenital Absence
Congenital Absence Of Kidney
Tissue Adhesions
Hereditary Diseases
Denys-drash Syndrome
Congenital Abnormality
Eye Abnormalities
Congenital Exomphalos

Carcinoma
Dysplasia
Malignant Neoplasms
Neoplasms
Multisystem Disorder
Haploinsufficiency
Congenital Cleft Nose

Pathways

Localization
Fin Development
Fin Morphogenesis
Pathogenesis
Kidney Development
Cell Adhesion
Cell Migration
Membrane Organization
Lung Development
Ossification

Mesenchymal Cell Migration
Basement Membrane Assembly
Translation
Organ Morphogenesis
Membrane Assembly

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FRAS1

References

PMID: 12766769 by McGregor L.K., et al. Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein.

PMID: 23473829 by Hoefele J., et al. Expanding the mutation spectrum for Fraser syndrome: identification of a novel heterozygous deletion in FRAS1.