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- Table of Contents
Facts about Forkhead box protein P1.
Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell regeneration and destiny by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development.
Human | |
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Gene Name: | FOXP1 |
Uniprot: | Q9H334 |
Entrez: | 27086 |
Belongs to: |
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No superfamily |
FLJ23741; fork head-related protein like B; forkhead box P1; forkhead box protein P1; FoxP1; glutamine-rich factor 1; hFKH1B; HSPC215; MGC12942; MGC88572; MGC99551; QRF1; QRF112CC4
Mass (kDA):
75.317 kDA
Human | |
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Location: | 3p13 |
Sequence: | 3; NC_000003.12 (70952817..71583989, complement) |
Isoform 8 is specifically expressed in embryonic stem cells.
Nucleus. Not found in the nucleolus.
PMID: 11751404 by Banham A.H., et al. The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.
PMID: 17344859 by Mullighan C.G., et al. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.