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Forkhead box protein M1 Antibodies
AND FOXM1 ELISA kits, Forkhead box protein M1 Proteins
Many biological assays use antibodies to detect Forkhead box protein M1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Forkhead box protein M1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Forkhead box protein M1 antibodies...
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FOXM1 Infographic by Boster Bio
All FOXM1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00659-3
100 µg/vial
Cat # A00659-3
100 µg/vial
FOXM1 Overview
Facts about Forkhead box protein M1.
Forkhead box protein M1 (FOXM1)
Transcriptional factor regulating the expression of cell cycle genes necessary for DNA replication and mitosis. Plays a role in the control of cell proliferation.
Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response. .
Gene Information
| Human | |
|---|---|
| Gene Name: | FOXM1 |
| Uniprot: | Q08050 |
| Entrez: | 2305 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
FKHL16; FKHL16trident; forkhead box M1; forkhead box protein M1; Forkhead, drosophila, homolog-like 16; forkhead-like 16; Forkhead-related protein FKHL16; FoxM1; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH-11; HFH11FOXM1B; HFH-11M-phase phosphoprotein 2; HNF-3; HNF-3/fork-head homolog 11; INS-1; MPHOSPH2; MPP-2; MPP2MPM-2 reactive phosphoprotein 2; PIG29; TGT3; Transcription factor Trident; Trident; WIN; Winged-helix factor from INS-1 cells
Molecular Weight
Mass (kDA):
84.283 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12p13.33 |
| Sequence: | 12; NC_000012.12 (2857680..2877174, complement) |
Tissue Specificity
Expressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Isoform 2 is highly expressed in testis.
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Cell Transformation, Neoplastic
- Malignant Neoplasm Of Breast
- Neoplasm Metastasis
- Cell Invasion
- Liver Carcinoma
- Neoplasm Invasiveness
- Mammary Neoplasms
- Liver Regeneration Disorder
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- CCNE1
- CDK6
- CTNNB1
- DARS
- FOXO3
- ORC2
- PES1
- ZC3H11A
Pathways
- Cell Cycle
- Cell Proliferation
- Mitosis
- Regeneration
- Cell Growth
- Dna Replication
- Cell Death
- Liver Regeneration
- Angiogenesis
- Cell Cycle Arrest
- S Phase
- Hepatocyte Proliferation
- Cell Differentiation
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Acetylation
Research Areas
- Cancer
- Mitotic Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FOXM1
bosterbio.com/bosterbio-gene-info-cards/FOXM1
References
PMID: 9032290 by Ye H., et al. Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues.
PMID: 9242644 by Yao K.-M., et al. Molecular analysis of a novel winged helix protein, WIN. Expression pattern, DNA binding property, and alternative splicing within the DNA binding domain.