Forkhead box protein H1 (FOXH1)

Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'.

Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Types a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 onto a site on the GSC promoter called TARE (TGF-beta/activin response component ).