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- Table of Contents
Facts about Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha.
May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. .
Human | |
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Gene Name: | FNTA |
Uniprot: | P49354 |
Entrez: | 2339 |
Belongs to: |
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protein prenyltransferase subunit alpha family |
CAAX farnesyltransferase subunit alpha; EC 2.5.1.58; EC 2.5.1.59; farnesyl-protein transferase alpha-subunit; farnesyltransferase, CAAX box, alpha; FPTA; FTase-alpha; GGTase-I-alpha; MGC99680; PGGT1A; protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; protein prenyltransferase alpha subunit repeat containing 2; PTAR2; Ras proteins prenyltransferase subunit alpha; type I protein geranyl-geranyltransferase alpha subunit; Type I protein geranyl-geranyltransferase subunit alpha
Mass (kDA):
44.409 kDA
Human | |
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Location: | 8p11.21 |
Sequence: | 8; NC_000008.11 (43056299..43085788) |
PMID: 8276393 by Andres D.A., et al. cDNA cloning of the two subunits of human CAAX farnesyltransferase and chromosomal mapping of FNTA and FNTB loci and related sequences.
PMID: 8419339 by Andres D.A., et al. Mutational analysis of alpha-subunit of protein farnesyltransferase. Evidence for a catalytic role.