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Facts about Formin-binding protein 1-like.
Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles.
Human | |
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Gene Name: | FNBP1L |
Uniprot: | Q5T0N5 |
Entrez: | 54874 |
Belongs to: |
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FNBP1 family |
C1orf39; chromosome 1 open reading frame 39; FLJ20275; formin binding protein 1-like; formin-binding protein 1-like; toca-1; TOCA1Transducer of Cdc42-dependent actin assembly protein 1; transducer of Cdc42-dependent actin assembly 1
Mass (kDA):
70.065 kDA
Human | |
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Location: | 1p22.1 |
Sequence: | 1; NC_000001.11 (93448067..93569671) |
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cytoplasmic vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
PMID: 15260990 by Ho H.-Y.H., et al. Toca-1 mediates Cdc42-dependent actin nucleation by activating the N- WASP-WIP complex.
PMID: 16326391 by Itoh T., et al. Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins.