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- Table of Contents
Facts about Flotillin-2.
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Human | |
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Gene Name: | FLOT2 |
Uniprot: | Q14254 |
Entrez: | 2319 |
Belongs to: |
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band 7/mec-2 family |
Epidermal surface antigen; ESA1Membrane component chromosome 17 surface marker 1; ESAchromosome 17, surface marker 1 (35kD protein identified bymonoclonal ECS-1); flotillin 2
Mass (kDA):
47.064 kDA
Human | |
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Location: | 17q11.2 |
Sequence: | 17; NC_000017.11 (28879339..28897733, complement) |
In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes.
Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Endosome. Membrane; Lipid-anchor. Membrane-associated protein of caveolae.
PMID: 8051082 by Schroeder W.T., et al. Cloning and characterization of a novel epidermal cell surface antigen (ESA).
PMID: 20682791 by Gorbea C., et al. A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.