FKBP5 Antibodies

AND FKBP5 ELISA kits, FKBP5 Proteins

Many biological assays use antibodies to detect FKBP5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FKBP5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FKBP5 antibodies...

We validate the specificity of these antibodies to FKBP5 by testing them on tissues known to express FKBP5 positively and negatively. Browse below to find the FKBP5 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FKBP5 Infographic by Boster Bio

All FKBP5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

FKBP5 FK506 Binding Protein 5 Human Recombinant Protein

Human

$250
Cat # PROTQ13451
2ug, 10ug, 1mg

Anti-FKBP51 Monoclonal Antibody

Human, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M04182
100 μl

Anti-FKBP5 Antibody

Human, Mouse, Rat

$405
Cat # A04182
100ul

Anti-FKBP51 Antibody

Human, Rat

Flow Cytometry, IP, IHC, WB

$405
Cat # A04182-1
100ul

Anti-FKBP51 (FKBP5) Mouse Monoclonal Antibody [Clone ID: OTI3E9]

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M04182-2
100 µl

FKBP51 (FKBP5) (NM_004117) Human Over-expression Lysate

Human

$628
Cat # LS002289
100 µg

FKBP5 Overview

Facts about Peptidyl-prolyl cis-trans isomerase FKBP5.

FKBP5 3D structure. Source: alphafold

Peptidyl-prolyl cis-trans isomerase FKBP5 (FKBP5)

Immunophilin protein with PPIase and co-chaperone actions. Part of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90).

Plays a role in the intracellular trafficking of heterooligomeric kinds of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded. .

Gene Information

Human
Gene Name:	FKBP5
Uniprot:	Q13451
Entrez:	2289

Family

Belongs to:

No superfamily

Alternative Names

51 kDa FKBP; 54 kDa progesterone receptor-associated immunophilin; AIG6,51 kDa FK506-binding protein; Androgen-regulated protein 6; Dit1; FF1 antigen; FK506 binding protein 5; FK506-binding protein 5; FKBP5; FKBP-5; FKBP51; FKBP-51; FKBP51PPIase FKBP5; FKBP54; FKBP54EC 5.2.1.8; HSP90-binding immunophilin; MGC111006; p54; P54,51 kDa FK506-binding protein 5; peptidyl-prolyl cis-trans isomerase FKBP5; peptidylprolyl cis-trans isomerase; PPIase; Ptg-10; rotamase; T-cell FK506-binding protein

Molecular Weight

Mass (kDA):
51.212 kDA

Genomic Context


Human

Location:	6p21.31
Sequence:	6; NC_000006.12 (35573585..35728583, complement)

Tissue Specificity

Widely expressed, enriched in testis compared to other tissues.

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

Depressive Disorder
Malignant Neoplasms
Post-traumatic Stress Disorder
Major Depressive Disorder
Neoplasms
Anxiety Disorders
Mood Disorders
Malignant Neoplasm Of Prostate
Stress, Psychological
Bipolar Disorder
Cancer Patients And Suicide And Depression
Prostatic Neoplasms

Mental Disorders
Physiological Stress
Depressive Symptom
Leukemia
Dysequilibrium Syndrome
Hypertensive Disease
Hyperplasia

Interacting Proteins

CDK15
CDK9
CHUK
HSP90AB1
KSR2

MOS
STK11
USP49

Pathways

Response To Antidepressant
Methylation
Dna Methylation
Pathogenesis
Transport
Immune Response
Sensitization
Cell Cycle
Cortisol Secretion
Cell Death
Cell Growth
Secretion
Cell Adhesion

Cell Proliferation
Protein Folding
Reverse Transcription
Localization
Neuroprotection
Dna Demethylation
Mammary Gland Development

PTMs

Phosphorylation
Methylation

Cleavage
Demethylation

Dephosphorylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FKBP5

References

PMID: 9125197 by Baughman G., et al. Tissue distribution and abundance of human FKBP51, an FK506-binding protein that can mediate calcineurin inhibition.

PMID: 9001212 by Nair S.C., et al. Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor.