FKBP1B Antibodies

AND FKBP1B ELISA kits, FKBP1B Proteins

Many biological assays use antibodies to detect FKBP1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FKBP1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FKBP1B antibodies...

We validate the specificity of these antibodies to FKBP1B by testing them on tissues known to express FKBP1B positively and negatively. Browse below to find the FKBP1B antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FKBP1B Infographic by Boster Bio

All FKBP1B Products

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Product

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Specificity

Applications

Price

Anti-FKBP1B Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A08125
100ul

Human FKBP12.6 Recombinant Protein

Enzyme Activity, SDS-PAGE

$250
Cat # PROTP68106
Starting from 20ug

FKBP1B (NM_054033) Human Over-expression Lysate

Human

$628
Cat # LS002281
100 µg

FKBP1B Overview

Facts about Peptidyl-prolyl cis-trans isomerase FKBP1B.

FKBP1B 3D structure. Source: alphafold

Peptidyl-prolyl cis-trans isomerase FKBP1B (FKBP1B)

Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins.

It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. .

Gene Information

Human
Gene Name:	FKBP1B
Uniprot:	P68106
Entrez:	2281

Family

Belongs to:

FKBP-type PPIase family

Alternative Names

12.6 kDa FK506-binding protein; calstabin 2,12.6 kDa FKBP; EC 5.2.1.8; FK506 binding protein 1B, 12.6 kDa; FK506-binding protein 12.6; FK506-binding protein 1B (12.6 kD); FK506-binding protein 1B; FKBP12.6; FKBP-12.6; FKBP12.6h-FKBP-12; FKBP1B; FKBP-1B; FKBP1L; FKBP9; Immunophilin FKBP12.6; OTK4; OTK4PPIase FKBP1B; peptidyl-prolyl cis-trans isomerase FKBP1B; PKBP1L; PPIase; rotamase

Molecular Weight

Mass (kDA):
11.783 kDA

Genomic Context


Human

Location:	2p23.3
Sequence:	2; NC_000002.12 (24033205..24067743)

Tissue Specificity

Detected in heart muscle (at protein level). Isoform 1 and isoform 2 are ubiquitous with highest levels in brain and thymus.

Subcellular Localizations

Cytoplasm. Sarcoplasmic reticulum.

Diseases

Severe Acute Respiratory Syndrome
Heart Diseases
Essential Hypertension
Cardiac Arrhythmia
Ventricular Tachycardia, Catecholaminergic Polymorphic, 1 (disorder)
Thyroid Diseases
Cardiomyopathy, Hypertrophic, Familial
Benign Prostatic Hypertrophy
Eye Abnormalities
Dental Plaque
Sudden Death
Dysequilibrium Syndrome
Hypertrophic Cardiomyopathy

Polymorphic Ventricular Tachycardia
Syncope
Coronavirus Infections
Prostatic Hyperplasia
Graves Disease
Premature Ventricular Contractions
Nervous System Disorder

Interacting Proteins

CAMK2D
KRT31
KRT40
REL
RYR2

TRIM69

Pathways

Senescence
Cell Activation
Organ Development
Aging
Pathogenesis
Transdifferentiation

Research Areas

mTOR Pathway
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FKBP1B

References

PMID: 7513996 by Arakawa H., et al. Molecular cloning and expression of a novel human gene that is highly homologous to human FK506-binding protein 12kDa (hFKBP-12) and characterization of two alternatively spliced transcripts.

PMID: 7592869 by Lam E., et al. A novel FK506 binding protein can mediate the immunosuppressive effects of FK506 and is associated with the cardiac ryanodine receptor.