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Fip1l1 Antibodies
AND Fip1l1 ELISA kits, Fip1l1 Proteins
Many biological assays use antibodies to detect Fip1l1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Fip1l1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Fip1l1 antibodies...
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Fip1l1 Infographic by Boster Bio
All Fip1l1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02452-1
100 μg/vial
Cat # A02452-1
100 μg/vial
Fip1l1 Overview
Facts about Pre-mRNA 3'-end-processing factor FIP1.
Pre-mRNA 3'-end-processing factor FIP1 (Fip1l1)
Part of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition.
Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex (By similarity).
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Fip1l1 |
| Uniprot: | Q9D824 |
| Entrez: | 66899 |
Family
| Belongs to: |
|---|
| FIP1 family |
Alternative Names
DKFZp586K0717; EC 1.1.1.86; EC 4.2.1.33; Factor interacting with PAP; FIP1 like 1 (S. cerevisiae); FIP1; FIP1-like 1 protein; FLJ33619; hFip1; pre-mRNA 3'-end-processing factor FIP1; Rearranged in hypereosinophilia; Rhe
Molecular Weight
Mass (kDA):
64.959 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 5|5 C3.3 |
| Sequence: | 5; |
Diseases
- Hypereosinophilic Syndrome
- Leukemia
- Eosinophilic Leukemia
- Chronic Eosinophilic Leukemia
- Idiopathic Hypereosinophilic Syndrome
- Eosinophilia
- Neoplasms
- Myeloproliferative Disease
- Malignant Neoplasms
- Myeloid Leukemia
- Myeloid Leukemia, Chronic
- Mastocytosis
Pathways
- Pathogenesis
- Reverse Transcription
- Eosinophil Development
- Cell Differentiation
- Interphase
- Cell Proliferation
- Cell Development
- Dendritic Cell Differentiation
- Hypersensitivity
- Localization
- Mrna Cleavage
- Methylation
PTMs
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Fip1l1
bosterbio.com/bosterbio-gene-info-cards/Fip1l1
References
PMID: 19224921 by Kiefer H., et al. Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation.