FHOD1 Antibodies

AND FHOD1 ELISA kits, FHOD1 Proteins

Many biological assays use antibodies to detect FHOD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FHOD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FHOD1 antibodies...

We validate the specificity of these antibodies to FHOD1 by testing them on tissues known to express FHOD1 positively and negatively. Browse below to find the FHOD1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FHOD1 Infographic by Boster Bio

All FHOD1 Products

Product

Figures

Specificity

Applications

Price

FHOD1 (NM_013241) Human Recombinant Protein

$1249
Cat # PROTQ9Y613
20 µg

FHOD1 (NM_013241) Human Over-expression Lysate

Human

$628
Cat # LS029109
100 µg

FHOD1 Overview

Facts about FH1/FH2 domain-containing protein 1.

FHOD1 3D structure. Source: alphafold

FH1/FH2 domain-containing protein 1 (FHOD1)

Required for the assembly of F-actin structures, such as stress fibers. Determined by the Rho-ROCK cascade for its action.

Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing.

Gene Information

Human
Gene Name:	FHOD1
Uniprot:	Q9Y613
Entrez:	29109

Family

Belongs to:

formin homology family

Alternative Names

FH1/FH2 domain-containing protein 1; FHOS1; FHOSFormin homolog overexpressed in spleen 1; formin homology 2 domain containing 1; Formin homology 2 domain-containing protein 1

Molecular Weight

Mass (kDA):
126.551 kDA

Genomic Context


Human

Location:	16q22.1
Sequence:	16; NC_000016.10 (67229389..67247481, complement)

Tissue Specificity

Ubiquitous. Highly expressed in spleen.

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, bleb. Predominantly cytoplasmic.

Diseases

Malignant Neoplasms
Chondrosarcoma
Neoplasms
Melanoma
Carcinogenesis
Malignant Neoplasm Of Pancreas
Cell Invasion
Glioblastoma
Myocardial Ischemia
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Breast Adenocarcinoma
Glaucoma, Open-angle

Parathyroid Neoplasms
Neoplasm Invasiveness
Carcinoid Tumor
Cardiovascular Diseases
Mammary Neoplasms
Meningioma
Bulla

Interacting Proteins

SYNE2

Pathways

Cell Migration
Cytokinesis
Localization
Actin Cytoskeleton Organization
Regulation Of Cytoskeleton
Glycosylation
Larval Development
Muscle Contraction
Cell Division
Cytoskeleton Organization
Mrna Splicing

Cell Motility
Limb Morphogenesis
Exocytosis
Rna Interference
Tissue Homeostasis

PTMs

Phosphorylation

Glycosylation

Cleavage

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FHOD1

References

PMID: 10352228 by Westendorf J.J., et al. Identification and characterization of a protein containing formin homology (FH1/FH2) domains.

PMID: 14576350 by Takeya R., et al. Fhos, a mammalian formin, directly binds to F-actin via a region N- terminal to the FH1 domain and forms a homotypic complex via the FH2 domain to promote actin fiber formation.