FGR Antibodies

AND FGR ELISA kits, FGR Proteins

Many biological assays use antibodies to detect FGR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FGR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FGR antibodies...

We validate the specificity of these antibodies to FGR by testing them on tissues known to express FGR positively and negatively. Browse below to find the FGR antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FGR Infographic by Boster Bio

All FGR Products

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Product

Figures

Specificity

Applications

Price

Anti-FGR Antibody Picoband®

3 Q&As

Human, Mouse, Rat

$370
Cat # A01674-1
100 μg/vial

Anti-Tyrosine-protein kinase Fgr FGR Antibody

Human

IHC, WB

$405
Cat # A01674
100ul

Anti-c-Fgr Antibody

Human, Mouse, Rat

ELISA, IHC-P, WB

$380
Cat # A01674-2
100ul

Anti-c-Fgr Monoclonal Antibody

Human, Mouse

ELISA, IHC, WB

$380
Cat # M01674
100ul

FGR (NM_005248) Human Recombinant Protein

$813
Cat # PROTP09769
20 µg

FGR (NM_005248) Human Over-expression Lysate

Human

$628
Cat # LS002268
100 µg

FGR Overview

Facts about Tyrosine-protein kinase Fgr.

FGR 3D structure. Source: alphafold

Tyrosine-protein kinase Fgr (FGR)

Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors devoid of kinase activity and contributes to the regulation of immune reactions, including neutrophil, monocyte, macrophage and mast cell functions, cytoskeleton remodeling in response to extracellular stimuli, phagocytosis, cell adhesion and migration. Acts downstream of receptors which bind the Fc region of immunoglobulins, such as MS4A2/FCER1B, FCGR2A and/or FCGR2B.

Acts downstream of ITGB1 and ITGB2, and regulates actin cytoskeleton reorganization, cell spreading and adhesion. Based on the circumstance, activates or inhibits cellular responses.

Gene Information

Human
Gene Name:	FGR
Uniprot:	P09769
Entrez:	2268

Family

Belongs to:

protein kinase superfamily

Alternative Names

c-fgr; c-src-2 proto-oncogene; c-src2; EC 2.7.10; EC 2.7.10.2; Fgr; FLJ43153; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; MGC75096; p55-c-fgr protein; p55c-fgr; p55-Fgr; p58c-fgr; Proto-oncogene c-Fgr; proto-oncogene tyrosine-protein kinase FGR; Src2; SRC2c-fgr protooncogene; tyrosine-protein kinase Fgr

Molecular Weight

Mass (kDA):
59.479 kDA

Genomic Context


Human

Location:	1p35.3
Sequence:	1; NC_000001.11 (27612064..27635561, complement)

Tissue Specificity

Detected in neutrophils, monocytes and natural killer cells (at protein level). Detected in monocytes and large lymphocytes.

Subcellular Localizations

Cell membrane; Lipid-anchor; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Mitochondrion inner membrane. Mitochondrion intermembrane space. Detected in mitochondrial intermembrane space and at inner membranes (By similarity). Colocalizes with actin fibers at membrane ruffles. Detected at plasma membrane lipid rafts.