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- Table of Contents
Facts about Fibroblast growth factor-binding protein 1.
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Human | |
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Gene Name: | FGFBP1 |
Uniprot: | Q14512 |
Entrez: | 9982 |
Belongs to: |
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fibroblast growth factor-binding protein family |
17 kDa heparin-binding growth factor-binding protein; FGFBP; FGF-BP; FGFBP1; FGF-BP1; FGFBP-1; FGFBPFGF-binding protein 1; fibroblast growth factor binding protein 1; fibroblast growth factor-binding protein 1; HBp17; HBP1717 kDa HBGF-binding protein; heparin-binding growth factor binding protein
Mass (kDA):
26.264 kDA
Human | |
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Location: | 4p15.32 |
Sequence: | 4; NC_000004.12 (15935577..15938740, complement) |
Expressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo- epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carcinomas (at protein level). Expressed in normal and wounded skin and various squamous cell carcinomas.
Secreted, extracellular space. Cell membrane; Peripheral membrane protein. Extracellular and plasma membrane-associated. Colocalizes with HSPG2 in the pericellular environment of squamous cell carcinomas.
PMID: 1885605 by Wu D.Q., et al. Characterization and molecular cloning of a putative binding protein for heparin-binding growth factors.
PMID: 9334727 by Czubayko F., et al. A secreted FGF-binding protein can serve as the angiogenic switch in human cancer.