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FGF23 Antibodies
AND FGF23 ELISA kits, FGF23 Proteins
Many biological assays use antibodies to detect FGF23, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FGF23 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FGF23 antibodies...
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FGF23 Infographic by Boster Bio
All FGF23 Products
Product
Figures
Specificity
Applications
Price
Mouse FGF23 ELISA Kit PicoKine®
14 Q&As
Mouse
ELISA
$450
Cat # EK1362
96 wells/kit, with removable strips.
Cat # EK1362
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK0759
96 wells/kit, with removable strips.
Cat # EK0759
96 wells/kit, with removable strips.
Rat FGF23 ELISA Kit PicoKine®
1 Citations 9 Q&As
Rat
ELISA
$499
Cat # EK1591
96 wells/kit, with removable strips.
Cat # EK1591
96 wells/kit, with removable strips.
Human
Cell Culture
$77
Cat # PROTQ9GZV9-5
5ug,20ug,100ug,500ug,1mg
Cat # PROTQ9GZV9-5
5ug,20ug,100ug,500ug,1mg
FGF23 Overview
Facts about Fibroblast growth factor 23.
Fibroblast growth factor 23 (FGF23)
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels.
Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to reduce PTH secretion (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | FGF23 |
| Uniprot: | Q9GZV9 |
| Entrez: | 8074 |
Family
| Belongs to: |
|---|
| heparin-binding growth factors family |
Alternative Names
ADHR; FGF23; FGF-23; fibroblast growth factor 23; HPDR2; HYPF; phosphatonin; PHPTC; tumor-derived hypophosphatemia inducing factor; Tumor-derived hypophosphatemia-inducing factor
Molecular Weight
Mass (kDA):
27.954 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12p13.32 |
| Sequence: | 12; NC_000012.12 (4368227..4379712, complement) |
Tissue Specificity
Expressed in osteogenic cells particularly during phases of active bone remodeling. In adult trabecular bone, expressed in osteocytes and flattened bone-lining cells (inactive osteoblasts).
Subcellular Localizations
Secreted. Secretion is dependent on O-glycosylation.
Diseases
- Kidney Diseases
- Hypophosphatemia
- Chronic Kidney Disease
- Rickets
- Hyperphosphatemia
- Osteomalacia
- Hypophosphatemic Rickets
- Kidney Failure, Chronic
- Familial Hypophosphatemic Bone Disease
- Hyperparathyroidism, Secondary
- Calcinosis
- Neoplasms
Interacting Proteins
- FGFR1
- Kl
Pathways
- Excretion
- Secretion
- Pathogenesis
- Transport
- Bone Mineralization
- Aging
- Glomerular Filtration
- Bone Remodeling
- Renal Phosphate Excretion
- Cell Proliferation
- Localization
- Glycosylation
- Intestinal Absorption
PTMs
- Cleavage
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FGF23
bosterbio.com/bosterbio-gene-info-cards/FGF23
References
PMID: 11032749 by Yamashita T., et al. Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain.
PMID: 11062477 by White K.E., et al. Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23.
2 Publications of Boster FGF23 Antibodies & ELISA Kits
- PubMed ID: 10.1155/2014/267808, The Role of Neurotrophic Factors Conjugated to Iron Oxide Nanoparticles in Perip...
- PubMed ID: 29399058, Ji KB, Ling L, Zhang Q, Chou JJ, Yang XL, Wang ZH, Yin L, Wu SF, Yu YF. Exp Ther...
*More publications can be found for each product on its corresponding product page