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- Table of Contents
, No Gclids
FCRL5 Antibodies
AND FCRL5 ELISA kits, FCRL5 Proteins
Many biological assays use antibodies to detect FCRL5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FCRL5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FCRL5 antibodies...
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FCRL5 Infographic by Boster Bio
All FCRL5 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1935
96 wells/kit, with removable strips.
Cat # EK1935
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1978
96 wells/kit, with removable strips.
Cat # EK1978
96 wells/kit, with removable strips.
FCRL5 Overview
Facts about Fc receptor-like protein 5.
Fc receptor-like protein 5 (FCRL5)
May be involved in B-cell growth and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. Might have an immunoregulatory role in marginal zone B-cells.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | FCRL5 |
| Uniprot: | Q96RD9 |
| Entrez: | 83416 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
BXMAS1; BXMAS1MGC119592; CD307; CD307e antigen; CD307e; DKFZp667E2019; DKFZp667F216; Fc receptor homolog 5; Fc receptor-like 5; Fc receptor-like protein 5; FcRH5; FCRH5MGC119593; FCRL5; FcR-like protein 5; FLJ00333; FLJ00397; IFGP5; Immune receptor translocation-associated protein 2; immunoglobulin superfamily receptor translocation associated 2 (IRTA2); IRTA2; IRTA2MGC119590; PRO820
Molecular Weight
Mass (kDA):
106.437 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q23.1 |
| Sequence: | 1; NC_000001.11 (157513377..157552533, complement) |
Tissue Specificity
Expressed in marginal zone B-cells, immunoblasts, tonsillar germinal center centrocytes and in the intraepithelial and interfollicular regions of the tonsil. Expressed in many lymphoma cell lines and on hairy cell leukemia cells. Isoform 1, isoform 3, isoform 4 and isoform 5 are detected in lymph node, spleen, bone marrow, and small intestine with preponderance of isoform 3. Expressed in mature and memory B-cells and down-regulated in germinal center cells (at protein level).
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Leukemia
- Malignant Neoplasms
- Neoplasms
- Chronic Lymphocytic Leukemia
- Multiple Myeloma
- Lymphoma
- Hairy Cell Leukemia
- Lymphoid Leukemia
- Burkitt Lymphoma
- Leukemogenesis
- Malignant Paraganglionic Neoplasm
- B-cell Lymphomas
- Chromosomal Translocation
Pathways
- Cell Development
- Cell Activation
- Cell Proliferation
- B Cell Proliferation
- B Cell Activation
- Reflex
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FCRL5
bosterbio.com/bosterbio-gene-info-cards/FCRL5
References
PMID: 11453668 by Nakayama Y., et al. BXMAS1 identifies a cluster of homologous genes differentially expressed in B cells.
PMID: 11290337 by Hatzivassiliou G., et al. IRTA1 and IRTA2, novel immunoglobulin superfamily receptors expressed in B cells and involved in chromosome 1q21 abnormalities in B cell malignancy.