Ficolin-3 Antibodies

AND FCN3 ELISA kits, Ficolin-3 Proteins

Many biological assays use antibodies to detect Ficolin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ficolin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ficolin-3 antibodies...

We validate the specificity of these antibodies to Ficolin-3 by testing them on tissues known to express FCN3 positively and negatively. Browse below to find the FCN3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FCN3 Infographic by Boster Bio

All FCN3 Products

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Product

Figures

Specificity

Applications

Price

Human Ficolin-3 ELISA Kit PicoKine®

9 Q&As

Human

ELISA

$499
Cat # EK1259
96 wells/kit, with removable strips.

Human Ficolin-3 PicoKine® Quick ELISA Kit

Human

ELISA

$499
Cat # FEK1259
96 wells/kit, with removable strips.

Anti-Ficolin-3 FCN3 Antibody

Human

ELISA, WB

$380
Cat # A04367
100ul

FCN3 (NM_003665) Human Over-expression Lysate

Human

$628
Cat # LS008547
100 µg

FCN3 Overview

Facts about Ficolin-3.

FCN3 3D structure. Source: alphafold

Ficolin-3 (FCN3)

May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin.

Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.

Gene Information

Human
Gene Name:	FCN3
Uniprot:	O75636
Entrez:	8547

Family

Belongs to:

ficolin lectin family

Alternative Names

FCN3; FCNH; Ficolin3; Ficolin-3; HAKA1; H-Ficolin

Molecular Weight

Mass (kDA):
32.903 kDA

Genomic Context


Human

Location:	1p36.11
Sequence:	1; NC_000001.11 (27369110..27374852, complement)

Tissue Specificity

Liver and lung. In liver it is produced by bile duct epithelial cells and hepatocytes. In lung it is produced by both ciliated bronchial epithelial cells and type II alveolar epithelial cells.

Subcellular Localizations

Secreted. Found in blood plasma, bronchus, alveolus and bile duct.

Diseases

Lupus Erythematosus, Systemic
Infective Disorder
Immunologic Deficiency Syndromes
Neoplasms
Bacteremia
Rheumatoid Arthritis
Respiratory Tract Infections
Arthritis
Autoimmunity
Malignant Neoplasms
Bacterial Infections
Inflammation
Infarction

Pneumonia
Stomach Neoplasms
Essential Hypertension
Malnutrition
Complement Deficiency
Non-neoplastic Disorder
Membranous Glomerulonephritis

Pathways

Complement Activation
Pathogenesis
Tissue Homeostasis

PTMs

Acetylation
Glycosylation

Cleavage
Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FCN3

References

PMID: 9694814 by Sugimoto R., et al. Cloning and characterization of the Hakata antigen, a member of the ficolin/opsonin p35 lectin family.

PMID: 10330454 by Akaiwa M., et al. Hakata antigen, a new member of the ficolin/opsonin p35 family, is a novel human lectin secreted into bronchus/alveolus and bile.