FCGRT Antibodies

IgG receptor FcRn large subunit p51 (FCGRT)

Binds to the Fc region of monomeric immunoglobulins gamma (PubMed:7964511, PubMed:10933786). Mediates the selective uptake of IgG from milk and assists newborn animals to acquire passive immunity.

IgG in the milk is bound at the apical surface of the intestinal epithelium. The consequent FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is discharged from FcRn into blood or tissue fluids (By similarity).

Gene Information

Human
Gene Name:	FCGRT
Uniprot:	P55899
Entrez:	2217

Family

Belongs to:
immunoglobulin superfamily

Alternative Names

alpha-chain; Fc fragment of IgG, receptor, transporter, alpha; FCGRT; FcRn alpha chain; FCRN; FCRNimmunoglobulin receptor, intestinal, heavy chain; IgG Fc fragment receptor transporter alpha chain; IgG receptor FcRn large subunit p51; major histocompatibility complex class I-like Fc receptor; Neonatal Fc receptor; neonatal Fc-receptor for Ig

Molecular Weight

Mass (kDA):
39.743 kDA

Genomic Context

Human
Location:	19q13.33
Sequence:	19; NC_000019.10 (49512661..49526428)

Tissue Specificity

Expressed in full-term placenta, heart, lung, liver, muscle, kidney, pancreas, and both fetal and adult small intestine.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Endosome membrane.

Diseases

• Variable Number Tandem Repeat
• Autoimmune Reaction
• Dysequilibrium Syndrome
• Common Variable Immunodeficiency
• Tetanus
• Neurofibromatosis 1
• Lupus Nephritis
• Autoimmune Diseases
• Glaucoma
• Blind Vision

• Intestinal Diseases
• Immunologic Deficiency Syndromes
• Disorder Of Eye
• Nephritis
• Lupus Erythematosus, Systemic

Pathways

• Transport
• Cytokine Production
• Dna Amplification
• Cell Death
• Localization

PTMs

• Disulfide bond

• Glycoprotein

• Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FCGRT

Boster Bio: Best Uses Of The FCGRT Marker

If you're looking for more information on Boster Bio: Best Uses of the FCGRT Marker, you're in the right site. This page will provide you with a quick overview of this revolutionary biosensor. Steven Boster's bio is available. Follow his advice to ensure that your experiment is as effective as possible. The FCGRT fluorescent marker is utilized in genetics research.

Boster Bio: FCGRT Marker

The FCGRT Marker is one of the most commonly used markers for lung research. It can be obtained through the use of esputo that is becoming widely used in diagnostic tests. This marker is particularly helpful for conditions that affect the respiratory tract, like asthma or bronquitis. The FCGRT Marker is a highly sensitive test for lung diseases and allows for precise diagnosis.

Boster Bio: Steven Boster

The FCGRT Marker is a protein that is used to identify the FCGRT receptor on human cells. It is highly sensitive and is suitable for a range of life sciences applications, such as research diagnostics, as well as drug discovery. It's also a great option to detect RNA and DNA strand breaks in cell cultures. Researchers can also use this marker to measure the FCGRT expression of the gene in cells.