FCGR2C Antibodies

AND FCGR2C ELISA kits, FCGR2C Proteins

Many biological assays use antibodies to detect FCGR2C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FCGR2C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FCGR2C antibodies...

We validate the specificity of these antibodies to FCGR2C by testing them on tissues known to express FCGR2C positively and negatively. Browse below to find the FCGR2C antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FCGR2C Infographic by Boster Bio

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Anti-CD32-C FCGR2C Antibody

Human, Mouse, Rat

$405
Cat # A08933
100ul

FCGR2C Overview

Facts about Low affinity immunoglobulin gamma Fc region receptor II-c.

FCGR2C 3D structure. Source: alphafold

Low affinity immunoglobulin gamma Fc region receptor II-c (FCGR2C)

Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor.

Involved in many different effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. .

Gene Information

Human
Gene Name:	FCGR2C
Uniprot:	P31995
Entrez:	9103

Family

Belongs to:

No superfamily

Alternative Names

Low affinity immunoglobulin gamma Fc region receptor II-c

Molecular Weight

Mass (kDA):
35.578 kDA

Genomic Context


Human

Location:	1q23.3
Sequence:	1; NC_000001.11 (161581339..161601220)

Tissue Specificity

Isoform IIC1 is detected in monocytes, macrophages, polymorphonuclear cells and natural killer cells.

Subcellular Localizations

[Isoform IIC4]: Cytoplasm.; [Isoform IIC3]: Cell membrane; Single-pass type I membrane protein.; [Isoform IIC2]: Cell membrane; Single-pass type I membrane protein.; [Isoform IIC1]: Cell membrane; Single-pass type I membrane protein.

Interacting Proteins

CRP
NCK1

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FCGR2C

References

PMID: 2531080 by Stuart S.G., et al. Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium.

PMID: 9516136 by Metes D., et al. Expression of functional CD32 molecules on human NK cells is determined by an allelic polymorphism of the FcgammaRIIC gene.