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FBXL5 Antibodies

AND FBXL5 ELISA kits, FBXL5 Proteins

Many biological assays use antibodies to detect FBXL5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FBXL5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FBXL5 antibodies...

We validate the specificity of these antibodies to FBXL5 by testing them on tissues known to express FBXL5 positively and negatively. Browse below to find the FBXL5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FBXL5 Infographic by Boster Bio

FBXL5 protein infographic

All FBXL5 Products

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Product

Figures

Specificity

Applications

Price

Anti-F-box/LRR-repeat protein 5 FBXL5 Antibody

Human

ELISA, WB

$405
Cat # A06215
100ul

FBXL5 (NM_012161) Human Over-expression Lysate

Human

$960
Cat # LS026234
100 µg

FBXL5 Overview

Facts about F-box/LRR-repeat protein 5.

FBXL5 3D structure

FBXL5 3D structure. Source: alphafold

F-box/LRR-repeat protein 5 (FBXL5)

Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by boosting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome.

Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued. .

Gene Information

Human
Gene Name:	FBXL5
Uniprot:	Q9UKA1
Entrez:	26234

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

FBL5FBL4F-box protein FBL5; F-box and leucine-rich repeat protein 5p45SKP2-like protein; F-box protein FBL4/FBL5; FLR1F-box/LRR-repeat protein 5

Molecular Weight

Mass (kDA):
78.555 kDA

Molecular Weight

Genomic Context


Human

Location:	4p15.32
Sequence:	4; NC_000004.12 (15604381..15681544, complement)

Subcellular Localizations

Cytoplasm, perinuclear region.

Subcellular Localization

Diseases

Hypoxia
Multiple Myeloma
Adverse Reaction To Iron And Iron Compounds (finding)
Steatohepatitis
Iron Overload
Liver Failure
Cytogenetic Abnormality
Liver Failure, Acute

Anoxia
Fatty Liver
Carcinoma

Disease

Interacting Proteins

SKP1

Interacting Proteins

Pathways

Transport
Proteolysis
Regulation Of Cell Cycle
Cell Cycle
Cell Cycle Phase
Mitotic Spindle Organization
G1 Phase
Spindle Organization

Protein Transport
Regulation Of Protein Stability

Pathways

PTMs

Ubiquitination

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FBXL5

References

PMID: 10531037 by Winston J.T., et al. A family of mammalian F-box proteins.

PMID: 10945468 by Ilyin G.P., et al. cDNA cloning and expression analysis of new members of the mammalian F-box protein family.