Fibrillin-3 Antibodies

AND FBN3 ELISA kits, Fibrillin-3 Proteins

Many biological assays use antibodies to detect Fibrillin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Fibrillin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Fibrillin-3 antibodies...

We validate the specificity of these antibodies to Fibrillin-3 by testing them on tissues known to express FBN3 positively and negatively. Browse below to find the FBN3 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: Chst3

FBN3 Infographic by Boster Bio

All FBN3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

FBN3 Overview

Facts about Fibrillin-3.

Fibrillin-3 (FBN3)

Fibrillin-3: Fibrillins are structural elements of 10- 12 nm extracellular calcium-binding microfibrils, which occur either in association with saliva or in elastin-free bundles. Fibrillin-containing microfibrils provide long-term force bearing structural support.

Gene Information

Human
Gene Name:	FBN3
Uniprot:	Q75N90
Entrez:	84467

Family

Belongs to:

fibrillin family

Alternative Names

fibrillin 3; fibrillin-3

Molecular Weight

Mass (kDA):
300.356 kDA

Genomic Context


Human

Location:	19p13.2
Sequence:	19; NC_000019.10 (8065402..8149592, complement)

Tissue Specificity

Predominantly expressed in connective tissues such as skeletal muscle, tendon, skin, perichondrium and periosteum. Highly expressed in fetal lung, brain, kidney. Expressed at low level in prostate, testis, mammary gland, uterus, ovary, placenta, bladder, adrenal gland, thyroid, fetal thymus, fetal liver, liver, fetal heart and heart.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Polycystic Ovary Syndrome
Marfan Syndrome
Congenital Contractural Arachnodactyly
Connective Tissue Diseases
Diabetes Mellitus
Insulin Resistance
Marfanoid Joint Hypermobility Syndrome
Endocrine System Diseases
Arachnodactyly
Aneurysm
Weill-marchesani Syndrome
Hereditary Diseases

Adolescent Idiopathic Scoliosis
Insulin Sensitivity
Diabetes Mellitus, Non-insulin-dependent
Malignant Neoplasms
Scoliosis, Unspecified
Malignant Neoplasm Of Ovary

Pathways

Localization
Glucose Homeostasis
Insulin Secretion
Menarche
Pathogenesis
Secretion

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FBN3

References

PMID: 14962672 by Corson G.M., et al. Differential expression of fibrillin-3 adds to microfibril variety in human and avian, but not rodent, connective tissues.

PMID: 15221638 by Uyeda T., et al. Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.