FASTK Antibodies

AND FASTK ELISA kits, FASTK Proteins

Many biological assays use antibodies to detect FASTK, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FASTK in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FASTK antibodies...

We validate the specificity of these antibodies to FASTK by testing them on tissues known to express FASTK positively and negatively. Browse below to find the FASTK antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: SPIN1

FASTK Infographic by Boster Bio

All FASTK Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-FAST FASTK Antibody

5 Q&As

Human, Mouse, Rat

$399
Cat # A09199
100μl

FASTK (NM_033015) Human Recombinant Protein

$1249
Cat # PROTQ14296
20 µg

FASTK (NM_006712) Human Over-expression Lysate

Human

$628
Cat # LS010922
100 µg

FASTK Overview

Facts about Fas-activated serine/threonine kinase.

FASTK 3D structure. Source: alphafold

Fas-activated serine/threonine kinase (FASTK)

Phosphorylates the splicing regulator TIA1, thereby promoting the addition of FAS exon 6, which contributes to an mRNA encoding a pro-apoptotic form of the receptor. .

Gene Information

Human
Gene Name:	FASTK
Uniprot:	Q14296
Entrez:	10922

Family

Belongs to:

FAST protein kinase family

Alternative Names

EC 2.7.11.8; Fas-activated serine/threonine kinase; FASTFAST kinase

Molecular Weight

Mass (kDA):
61.104 kDA

Genomic Context


Human

Location:	7q36.1
Sequence:	7; NC_000007.14 (151076621..151080883, complement)

Tissue Specificity

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Subcellular Localizations

[Isoform 4]: Mitochondrion matrix. Colocalizes with mitochondrial RNA granules.

Diseases

Malignant Neoplasms
Neoplasms
Retinal Degeneration
Lymphoma, T-cell, Cutaneous
Cardiovascular Diseases
Carcinoma, Pancreatic Ductal
Pancreatic Neoplasm
Lymphoma
Malignant Neoplasm Of Ovary
Mycoses
Malignant Neoplasm Of Pancreas

Cytogenetic Abnormality
T-cell Lymphoma
Mycosis Fungoides
Infective Disorder
Adult T-cell Lymphoma/leukemia
Nerve Degeneration

Interacting Proteins

PRPF31
WIPF1

Pathways

Cell Death
Regeneration
Pathogenesis
Rna Interference

PTMs

Phosphorylation

Dephosphorylation

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FASTK

References

PMID: 7544399 by Tian Q., et al. Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis.

PMID: 17135269 by Izquierdo J.M., et al. Fas-activated serine/threonine kinase (FAST K) synergizes with TIA- 1/TIAR proteins to regulate Fas alternative splicing.