Centrosome-associated protein 350 (CEP350)

Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ (PubMed:19052644). Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network (PubMed:16314388, PubMed:17878239, PubMed:28659385).

Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA action (PubMed:15615782). Required for ciliation (PubMed:28659385).