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- Table of Contents
Facts about E3 ubiquitin-protein ligase FANCL.
May stimulate the ubiquitin release from UBE2W. May be required for appropriate primordial germ cell proliferation in the embryonic phase, whereas it is probably not needed for spermatogonial proliferation after birth.
Human | |
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Gene Name: | FANCL |
Uniprot: | Q9NW38 |
Entrez: | 55120 |
Belongs to: |
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No superfamily |
E3 ubiquitin-protein ligase FANCL; EC 6.3.2.-; FAAP43PHF9FLJ10335; Fanconi anemia group L protein; Fanconi anemia, complementation group L; Fanconi anemia-associated polypeptide of 43 kDa; PHD finger protein 9; Pog
Mass (kDA):
42.905 kDA
Human | |
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Location: | 2p16.1 |
Sequence: | 2; NC_000002.12 (58159243..58241681, complement) |
Cytoplasm. Nucleus.
PMID: 12724401 by Meetei A.R., et al. A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome.
PMID: 12973351 by Meetei A.R., et al. A novel ubiquitin ligase is deficient in Fanconi anemia.