FANCI Antibodies

AND FANCI ELISA kits, FANCI Proteins

Many biological assays use antibodies to detect FANCI, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FANCI in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FANCI antibodies...

We validate the specificity of these antibodies to FANCI by testing them on tissues known to express FANCI positively and negatively. Browse below to find the FANCI antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FANCI Infographic by Boster Bio

All FANCI Products

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Specificity

Applications

Price

Anti-Phospho-FANCI (Ser556) Antibody

1 Q&As

Human

$481
Cat # P05108
100 µl

Anti-Fanconi anemia group I protein FANCI Antibody

Human

$405
Cat # A05108
100ul

FANCI Overview

Facts about Fanconi anemia group I protein.

FANCI 3D structure. Source: alphafold

Fanconi anemia group I protein (FANCI)

Plays an essential role in the repair of DNA double- strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by encouraging FANCD2 monoubiquitination by FANCL and engaging in recruitment to DNA repair sites. Required for maintenance of chromosomal stability.

Specifically binds branched DNA: binds both single- stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage.

Gene Information

Human
Gene Name:	FANCI
Uniprot:	Q9NVI1
Entrez:	55215

Family

Belongs to:

No superfamily

Alternative Names

Fanconi anemia group I protein; Fanconi anemia, complementation group I; KIAA1794FLJ10719; Protein FACI

Molecular Weight

Mass (kDA):
149.324 kDA

Genomic Context


Human

Location:	15q26.1
Sequence:	15; NC_000015.10 (89243973..89317259)

Subcellular Localizations

Nucleus. Observed in spots localized in pairs on the sister chromatids of mitotic chromosome arms and not centromeres, one on each chromatids. These foci coincide with common fragile sites. They are frequently interlinked through BLM-associated ultra-fine DNA bridges.