FANCD2 Antibodies

AND FANCD2 ELISA kits, FANCD2 Proteins

Many biological assays use antibodies to detect FANCD2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FANCD2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FANCD2 antibodies...

We validate the specificity of these antibodies to FANCD2 by testing them on tissues known to express FANCD2 positively and negatively. Browse below to find the FANCD2 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FANCD2 Infographic by Boster Bio

All FANCD2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-FANCD2 Antibody

7 Q&As

Human, Mouse, Rat

$399
Cat # A00563
100μl

Anti-FANCD2 Rabbit Monoclonal Antibody

1 Q&As

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$370
Cat # M00563
100 μl

FANCD2 Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$480
Cat # EKC1208
1 kit, containing one 96-well plate and all necessary reagents

FANCD2 (Phospho-Ser222) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2032
1 kit, containing two 96-well plates and all necessary reagents

Anti-FANCD2 (P216) Antibody

Human, Mouse, Rat

IHC

$405
Cat # A00563-1
100ul

Anti-FANCD2 Antibody

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$405
Cat # A00563-2
100ul

Anti-Phospho-FANCD2 (S222) Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A00563S222
100ul

FANCD2 Overview

Facts about Fanconi anemia group D2 protein.

FANCD2 3D structure. Source: alphafold

Fanconi anemia group D2 protein (FANCD2)

Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis.

Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage.

Gene Information

Human
Gene Name:	FANCD2
Uniprot:	Q9BXW9
Entrez:	2177

Family

Belongs to:

No superfamily

Alternative Names

DKFZp762A223; FA4; FACD; FACDFLJ23826; FAD; FAD2; FA-D2; FADFAD2; FANCD; FANCD2; Fanconi anemia group D2 protein; Fanconi anemia, complementation group D2; Protein FACD2

Molecular Weight

Mass (kDA):
164.128 kDA

Genomic Context


Human

Location:	3p25.3
Sequence:	3; NC_000003.12 (10026437..10101932)

Tissue Specificity

Highly expressed in germinal center cells of the spleen, tonsil, and reactive lymph nodes, and in the proliferating basal layer of squamous epithelium of tonsil, esophagus, oropharynx, larynx and cervix. Expressed in cytotrophoblastic cells of the placenta and exocrine cells of the pancreas (at protein level). Highly expressed in testis, where expression is restricted to maturing spermatocytes.

Subcellular Localizations

Nucleus. Concentrates in nuclear foci during S phase and upon genotoxic stress. At the onset of mitosis, excluded from chromosomes and diffuses into the cytoplasm, returning to the nucleus at the end of cell division. Observed in a few spots localized in pairs on the sister chromatids of mitotic chromosome arms and not centromeres, one on each chromatids. These foci coincide with common fragile sites and could be sites of replication fork stalling. The foci are frequently interlinked through BLM-associated ultra-fine DNA bridges. Following aphidicolin treatment, targets chromatid gaps and brea