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- Table of Contents
Facts about Leucine repeat adapter protein 25.
LRAP25-mediated CDC42BPA/CDC42BPB targeting to LIMK1 and the lamellipodium results in LIMK1 activation and the subsequent phosphorylation of CFL1 that's important for lamellipodial F- actin regulation (PubMed:25107909). .
Mouse | |
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Gene Name: | Fam89b |
Uniprot: | Q9QUI1 |
Entrez: | 17826 |
Belongs to: |
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FAM89 family |
family with sequence similarity 89, member B; mammary tumor virus receptor homolog 1; MTVR1
Mass (kDA):
20.14 kDA
Mouse | |
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Location: | 19 A|19 4.34 cM |
Sequence: | 19; |
Widely expressed. Expressed in the early postnatal brain.
PMID: 10512749 by Sakuma-Takagi M., et al. Novel related cDNAs (C184L, C184M, and C184S) from developing mouse brain encoding two apparently unrelated proteins.
PMID: 9525630 by Golovkina T.V., et al. A novel membrane protein is a mouse mammary tumor virus receptor.