EFTUD2 Antibodies

AND EFTUD2 ELISA kits, EFTUD2 Proteins

Many biological assays use antibodies to detect EFTUD2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EFTUD2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EFTUD2 antibodies...

We validate the specificity of these antibodies to EFTUD2 by testing them on tissues known to express EFTUD2 positively and negatively. Browse below to find the EFTUD2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EFTUD2 Infographic by Boster Bio

All EFTUD2 Products

Product

Figures

Specificity

Applications

Price

Anti-Snrp116 EFTUD2 Antibody

13 Q&As

Human, Mouse

$399
Cat # A04780
100μl

EFTUD2 (NM_004247) Human Recombinant Protein

$1249
Cat # PROTQ15029
20 µg

EFTUD2 (NM_004247) Human Over-expression Lysate

Human

$628
Cat # LS009343
100 µg

EFTUD2 Overview

Facts about 116 kDa U5 small nuclear ribonucleoprotein component.

EFTUD2 3D structure. Source: alphafold

116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2)

Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex necessary for pre-mRNA splicing. Binds GTP.

Gene Information

Human
Gene Name:	EFTUD2
Uniprot:	Q15029
Entrez:	9343

Family

Belongs to:

TRAFAC class translation factor GTPase superfamily

Alternative Names

DKFZp686E24196; elongation factor Tu GTP binding domain containing 2; Elongation factor Tu GTP-binding domain-containing protein 2; FLJ44695; hSNU114; KIAA0031U5-116 kDa; SNRP116; Snrp116,116 kDa U5 small nuclear ribonucleoprotein component; SNU114 homolog; Snu114; U5 snRNP specific protein, 116 kD; U5 snRNP-specific protein, 116 kD; U5 snRNP-specific protein, 116 kDa; U5-116KD

Molecular Weight

Mass (kDA):
109.436 kDA

Genomic Context


Human

Location:	17q21.31
Sequence:	17; NC_000017.11 (44849948..44899625, complement)

Subcellular Localizations

Nucleus.

Diseases

Microcephaly
Atresia
Dysostoses
Mandibulofacial Dysostosis
Charge Syndrome
Cleft Palate
Haploinsufficiency
Choanal Atresia
Hereditary Diseases
Congenital Abnormality
Developmental Delay (disorder)
Major Anomalies Of Jaw Size, Mandibular Hypoplasia
Dermoid Cyst

Sequelae Aspects
Esophageal Atresia
Congenital Small Ears
Age Related Macular Degeneration
Hypoplasia
Genetic Diseases, Inborn
Goldenhar Syndrome With Ipsilateral Radial Defect

Interacting Proteins

HSPB1
IK
MYC
PRPF8
SF3B4

SNRNP40

PTMs

Acetylation
Isopeptide bond

Phosphoprotein
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EFTUD2

References

PMID: 9233818 by Fabrizio P., et al. An evolutionarily conserved U5 snRNP-specific protein is a GTP- binding factor closely related to the ribosomal translocase EF-2.

PMID: 9774689 by Achsel T., et al. The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein.