Efhc1 Antibodies

AND Efhc1 ELISA kits, Efhc1 Proteins

Many biological assays use antibodies to detect Efhc1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Efhc1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Efhc1 antibodies...

We validate the specificity of these antibodies to Efhc1 by testing them on tissues known to express Efhc1 positively and negatively. Browse below to find the Efhc1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Efhc1 Infographic by Boster Bio

All Efhc1 Products

Product

Figures

Specificity

Applications

Price

Anti-EFHC1 Antibody

Human, Mouse, Rat

$405
Cat # A05955
100ul

EFHC1 (NM_018100) Human Recombinant Protein

$1249
Cat # PROTQ5JVL4
20 µg

Efhc1 Overview

Facts about EF-hand domain-containing protein 1.

EF-hand domain-containing protein 1 (Efhc1)

Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization.

Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration (By similarity). May enhance calcium influx through CACNA1E and stimulate programmed cell death.

Gene Information

Mouse
Gene Name:	Efhc1
Uniprot:	Q9D9T8
Entrez:	71877

Family

Belongs to:

No superfamily

Alternative Names

dJ304B14.2; EF-hand domain (C-terminal) containing 1; EF-hand domain-containing protein 1; EJA1; EJM1; FLJ10466; FLJ37290; JAE; myoclonin-1

Molecular Weight

Mass (kDA):
75.142 kDA

Genomic Context


Mouse

Location:	1\|1 A4
Sequence:	1;

Diseases

Epilepsy
Myoclonic Epilepsy, Juvenile
Epilepsies, Myoclonic
Epilepsy, Generalized
Absence Epilepsy
Idiopathic Generalized Epilepsy
Febrile Convulsions
Nervous System Disorder
Familial Benign Neonatal Epilepsy
Generalized Seizures
Convulsion Neonatal
Convulsions

Infantile Severe Myoclonic Epilepsy
Myoclonus
Channelopathies
Intractable Epilepsy
Reperfusion Injury
Malnutrition
Spinal Cord Injuries

Pathways

Brain Development
Cell Division
Pathogenesis
Localization
Mitotic Spindle Organization
Spindle Organization
Cell Migration
Insulin Secretion
Mitosis
Synaptic Transmission
M Phase
Cytokinesis
Regeneration

Cell Cycle
Cell Death
Locomotion
Interphase
Exocytosis
Regulation Of Cell Division
Secretion

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Efhc1

References

PMID: 15258581 by Suzuki T., et al. Mutations in EFHC1 cause juvenile myoclonic epilepsy.

PMID: 15670853 by Ikeda T., et al. The mouse ortholog of EFHC1 implicated in juvenile myoclonic epilepsy is an axonemal protein widely conserved among organisms with motile cilia and flagella.