Protein eyes shut homolog Antibodies

AND EYS ELISA kits, Protein eyes shut homolog Proteins

Many biological assays use antibodies to detect Protein eyes shut homolog, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein eyes shut homolog in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein eyes shut homolog antibodies...

We validate the specificity of these antibodies to Protein eyes shut homolog by testing them on tissues known to express EYS positively and negatively. Browse below to find the EYS antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EYS Infographic by Boster Bio

All EYS Products

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Product

Figures

Specificity

Applications

Price

Anti-Zebrafish EYS Antibody

Zebrafish

$470
Cat # DZ06950-1
200 μl/vial

EYS (NM_198283) Human Over-expression Lysate

Human

$960
Cat # LS346007
100 µg

EYS Overview

Facts about Protein eyes shut homolog.

Protein eyes shut homolog (EYS)

Required to maintain the integrity of photoreceptor cells. .

Gene Information

Human
Gene Name:	EYS
Uniprot:	Q5T1H1
Entrez:	346007

Family

Belongs to:

EYS family

Alternative Names

C6orf178; C6orf179; C6orf180; dJ22I17.2; dJ303F19.1; EGFL10; EGFL11; EGF-like-domain, multiple 10; EGF-like-domain, multiple 11; eyes shut homolog (Drosophila); protein spacemaker homolog

Molecular Weight

Mass (kDA):
350.796 kDA

Genomic Context


Human

Location:	6q12
Sequence:	6; NC_000006.12 (63719980..65707226, complement)

Tissue Specificity

Present in retina.

Subcellular Localizations

Cell projection, cilium, photoreceptor outer segment. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix. Localizes to discrete puncta at, or adjacent to, the photoreceptor connecting cilium (PubMed:27737822). Highly expressed in cone photoreceptor outer segments (PubMed:27737822). Weakly expressed in rod photoreceptor outer segments (By similarity). May localize to the cilium axoneme (PubMed:27846257). May also be secreted into the i

Diseases

Retinitis Pigmentosa
Dystrophy
Retinal Dystrophies
Retinal Diseases
Night Blindness
Glaucoma
Blind Vision
Hypertensive Disease
Amaurosis
Iritis
Stenosis
Retinal Degeneration

Degenerative Disorder
Glaucoma, Open-angle
Stargardt's Disease
Vitelliform Macular Dystrophy
Rheumatism
Myopathy

Pathways

Pathogenesis
Notch Signaling Pathway
Regeneration
Secretion

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EYS

References

PMID: 18976725 by Collin R.W.J., et al. Identification of a 2 Mb human ortholog of Drosophila eyes shut/spacemaker that is mutated in patients with retinitis pigmentosa.

PMID: 18836446 by Abd El-Aziz M.M., et al. EYS, encoding an ortholog of Drosophila spacemaker, is mutated in autosomal recessive retinitis pigmentosa.