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- Table of Contents
Facts about Exocyst complex component 2.
Human | |
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Gene Name: | EXOC2 |
Uniprot: | Q96KP1 |
Entrez: | 55770 |
Belongs to: |
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SEC5 family |
exocyst complex component 2; Exocyst complex component Sec5; FLJ11026; SEC5; SEC5L1; SEC5-like 1 (S. cerevisiae); SEC5-like 1; Sec5p
Mass (kDA):
104.066 kDA
Human | |
---|---|
Location: | 6p25.3 |
Sequence: | 6; NC_000006.12 (485138..693141, complement) |
Widely expressed with highest levels in brain and placenta.
Midbody, Midbody ring. Recruitment to the midbody does not require RALA, nor RALB (PubMed:18756269). Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214).
PMID: 12459492 by Sjoelinder M., et al. DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion.
PMID: 16213214 by Gromley A., et al. Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission.