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- Table of Contents
Facts about Protein C-ets-1.
May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell invasion and migration.
Human | |
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Gene Name: | ETS1 |
Uniprot: | P14921 |
Entrez: | 2113 |
Belongs to: |
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ETS family |
Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1; ets protein; Ets1; Ets-1; EWSR2; FLJ10768; p54; Protein C-Ets-1; v-ets avian erythroblastosis virus E2 oncogene homolog 1; v-ets avian erythroblastosis virus E26 oncogene homolog 1; v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); v-ets
Mass (kDA):
50.408 kDA
Human | |
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Location: | 11q24.3 |
Sequence: | 11; NC_000011.10 (128458761..128587593, complement) |
Highly expressed within lymphoid cells. Isoforms c-ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in adult tissues. None is detected in brain or kidney.
Cytoplasm. Nucleus. Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27.
PMID: 3060801 by Reddy E.S.P., et al. Structure, expression and alternative splicing of the human c-ets-1 proto-oncogene.
PMID: 2847145 by Watson D.K., et al. Mammalian ets-1 and ets-2 genes encode highly conserved proteins.
*More publications can be found for each product on its corresponding product page